acetic acid 4-(2-tert-butoxycarbonylaminoethyl)phenyl ester

Base Information

• Chemical Name: acetic acid 4-(2-tert-butoxycarbonylaminoethyl)phenyl ester
• CAS No.: 1133218-19-5
• Molecular Formula: C₁₅H₂₁NO₄
• Molecular Weight: 279.336
• Mol file: 1133218-19-5.mol

Synonyms:acetic acid 4-(2-tert-butoxycarbonylaminoethyl)phenyl ester

Chemical Property of acetic acid 4-(2-tert-butoxycarbonylaminoethyl)phenyl ester

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of acetic acid 4-(2-tert-butoxycarbonylaminoethyl)phenyl ester

There total 2 articles about acetic acid 4-(2-tert-butoxycarbonylaminoethyl)phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

di-tert-butyl dicarbonate (24424-99-5) + 4-(2-aminoethyl)-phenyl acetate (20284-85-9) → acetic acid 4-(2-tert-butoxycarbonylaminoethyl)phenyl ester (1133218-19-5)

Guidance literature:

at 20 ℃; for 0.166667h; Ionic liquid;

DOI:10.14233/ajchem.2017.20479

Reference yield:

N-t-butoxycarbonyl-tyramine (64318-28-1) + acetyl chloride (75-36-5) → acetic acid 4-(2-tert-butoxycarbonylaminoethyl)phenyl ester (1133218-19-5)

Guidance literature:

With triethylamine; In tetrahydrofuran; at 20 ℃; for 2h; Inert atmosphere;

DOI:10.1016/j.tet.2008.12.052

Reference yield:

acetic acid 4-(2-tert-butoxycarbonylaminoethyl)phenyl ester (1133218-19-5) → 4-(2-aminoethyl)-phenyl acetate (20284-85-9)

Guidance literature:

acetic acid 4-(2-tert-butoxycarbonylaminoethyl)phenyl ester; With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 0.5h;

With Amberlyst 15; In dichloromethane; for 1h;

DOI:10.1016/j.tet.2008.12.052

upstream raw materials:

N-t-butoxycarbonyl-tyramine

acetyl chloride

di-tert-butyl dicarbonate

4-(2-aminoethyl)-phenyl acetate

Downstream raw materials:

4-(2-aminoethyl)-phenyl acetate