4-Chloropyridine-2,6-dicarbohydrazide

Base Information

• Chemical Name: 4-Chloropyridine-2,6-dicarbohydrazide
• CAS No.: 98276-29-0
• Molecular Formula: C7H8ClN5O2
• Molecular Weight: 229.626
• Hs Code.: 2933399090
• Mol file: 98276-29-0.mol

Synonyms:NSC 41775;

Chemical Property of 4-Chloropyridine-2,6-dicarbohydrazide

Chemical Property:

• PSA: 126.62000
• Density: 1.534 g/cm³
• LogP: 1.30830

Purity/Quality:

97% ^*data from raw suppliers

4-Chloropyridine-2,6-dicarbohydrazide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-Chloropyridine-2,6-dicarbohydrazide

There total 1 articles about 4-Chloropyridine-2,6-dicarbohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diethyl 4-chloropyridine-2,6-dicarboxylate (53389-01-8) → (4-chloropyridine-2,6-diyl)bisdihydrazide (98276-29-0)

Guidance literature:

With ethanol; hydrazine hydrate;

DOI:10.1021/ja01597a074

Reference yield:

(4-chloropyridine-2,6-diyl)bisdihydrazide (98276-29-0) → 4-chloropyridine-2,6-diylcarboxylic acid diazide (121572-36-9)

Guidance literature:

With hydrogenchloride; sodium nitrite; In water; for 1h; Ambient temperature;

DOI:10.1021/jm00130a023

Reference yield:

(4-chloropyridine-2,6-diyl)bisdihydrazide (98276-29-0) → 4-Chloro-6-methoxycarbonylamino-pyridine-2-carboxylic acid methyl ester (121572-38-1)

Guidance literature:

Multi-step reaction with 2 steps

1: NaNO₂, 10percent HCl / H₂O / 1 h / Ambient temperature

2: 8 h / Heating

With hydrogenchloride; sodium nitrite; In water;

DOI:10.1021/jm00130a023

upstream raw materials:

diethyl 4-chloropyridine-2,6-dicarboxylate

Downstream raw materials:

N,N'-(4-chloro-pyridine-2,6-diyl)-bis-carbamic acid diethyl ester

N,N'-(4-chloro-pyridine-2,6-diyl)-bis-carbamic acid diisopropyl ester

4-chloropyridine-2,6-diylcarboxylic acid diazide

Cl₂popp