2-oxo-3-[α-[N-(tert-butoxycarbonyl)-O-(tert-butyl)]-L-γ-glutamyl]thiazolidine-4(R)-carboxylic acid phenacyl ester

Base Information

Chemical Name:2-oxo-3-[α-[N-(tert-butoxycarbonyl)-O-(tert-butyl)]-L-γ-glutamyl]thiazolidine-4(R)-carboxylic acid phenacyl ester
CAS No.:255057-31-9
Molecular Formula:C₂₆H₃₄N₂O₉S
Molecular Weight:550.63
Hs Code.:

Synonyms:2-oxo-3-[α-[N-(tert-butoxycarbonyl)-O-(tert-butyl)]-L-γ-glutamyl]thiazolidine-4(R)-carboxylic acid phenacyl ester

Suppliers and Price of 2-oxo-3-[α-[N-(tert-butoxycarbonyl)-O-(tert-butyl)]-L-γ-glutamyl]thiazolidine-4(R)-carboxylic acid phenacyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-oxo-3-[α-[N-(tert-butoxycarbonyl)-O-(tert-butyl)]-L-γ-glutamyl]thiazolidine-4(R)-carboxylic acid phenacyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-oxo-3-[α-[N-(tert-butoxycarbonyl)-O-(tert-butyl)]-L-γ-glutamyl]thiazolidine-4(R)-carboxylic acid phenacyl ester

There total 2 articles about 2-oxo-3-[α-[N-(tert-butoxycarbonyl)-O-(tert-butyl)]-L-γ-glutamyl]thiazolidine-4(R)-carboxylic acid phenacyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 81659-82-7
N-α-tert-butoxycarbonyl-L-glutamic acid γ-N-succinimidyl ester α-tert-butyl ester

: (R)-2-Oxo-thiazolidine-4-carboxylic acid 2-oxo-2-phenyl-ethyl ester

: 255057-31-9
2-oxo-3-[α-[N-(tert-butoxycarbonyl)-O-(tert-butyl)]-L-γ-glutamyl]thiazolidine-4(R)-carboxylic acid phenacyl ester

Guidance literature:: With dmap; triethylamine; at 50 ℃; for 48h;
DOI:10.1021/jm980289j

Reference yield:

: 70-11-1
α-bromoacetophenone

: 255057-31-9
2-oxo-3-[α-[N-(tert-butoxycarbonyl)-O-(tert-butyl)]-L-γ-glutamyl]thiazolidine-4(R)-carboxylic acid phenacyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / Et₃N / 20 °C

2: 65 percent / Et₃N; DMAP / 48 h / 50 °C

With dmap; triethylamine; 1: Esterification / 2: Condensation;
DOI:10.1021/jm980289j