2-[4-[(4-chlorophenyl)thio]-1-(4-fluorophenyl)-1H-pyrazol-3-yl]-5-(1,3,4-oxadiazol-2-yl)pyrazine

Base Information

Chemical Name:2-[4-[(4-chlorophenyl)thio]-1-(4-fluorophenyl)-1H-pyrazol-3-yl]-5-(1,3,4-oxadiazol-2-yl)pyrazine
CAS No.:1199802-40-8
Molecular Formula:C₂₁H₁₂ClFN₆OS
Molecular Weight:450.883
Hs Code.:

Synonyms:2-[4-[(4-chlorophenyl)thio]-1-(4-fluorophenyl)-1H-pyrazol-3-yl]-5-(1,3,4-oxadiazol-2-yl)pyrazine

Suppliers and Price of 2-[4-[(4-chlorophenyl)thio]-1-(4-fluorophenyl)-1H-pyrazol-3-yl]-5-(1,3,4-oxadiazol-2-yl)pyrazine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-[4-[(4-chlorophenyl)thio]-1-(4-fluorophenyl)-1H-pyrazol-3-yl]-5-(1,3,4-oxadiazol-2-yl)pyrazine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-[4-[(4-chlorophenyl)thio]-1-(4-fluorophenyl)-1H-pyrazol-3-yl]-5-(1,3,4-oxadiazol-2-yl)pyrazine

There total 4 articles about 2-[4-[(4-chlorophenyl)thio]-1-(4-fluorophenyl)-1H-pyrazol-3-yl]-5-(1,3,4-oxadiazol-2-yl)pyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₀H₁₄ClFN₆OS

: 122-51-0
orthoformic acid triethyl ester

: 1199802-40-8
2-[4-[(4-chlorophenyl)thio]-1-(4-fluorophenyl)-1H-pyrazol-3-yl]-5-(1,3,4-oxadiazol-2-yl)pyrazine

Guidance literature:: With trifluoroacetic acid; at 120 ℃; for 0.25h; Microwave irradiation;

Reference yield:

: 106-54-7
p-Chlorothiophenol

: 1199802-40-8
2-[4-[(4-chlorophenyl)thio]-1-(4-fluorophenyl)-1H-pyrazol-3-yl]-5-(1,3,4-oxadiazol-2-yl)pyrazine

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydride / 1-methyl-pyrrolidin-2-one / 0.25 h / 20 °C

1.2: 0.17 h / 150 °C / Microwave irradiation

2.1: hydrazine / ethanol / 80 °C

3.1: trifluoroacetic acid / 0.25 h / 120 °C / Microwave irradiation

With sodium hydride; trifluoroacetic acid; hydrazine; In 1-methyl-pyrrolidin-2-one; ethanol;

Reference yield:

: 1199804-68-6
methyl 5-[4-[(4-chlorophenyl)thio]-1-(4-fluorophenyl)-1H-pyrazol-3-yl]-2-pyrazinecarboxylate

: 1199802-40-8
2-[4-[(4-chlorophenyl)thio]-1-(4-fluorophenyl)-1H-pyrazol-3-yl]-5-(1,3,4-oxadiazol-2-yl)pyrazine

Guidance literature:: Multi-step reaction with 2 steps

1: hydrazine / ethanol / 80 °C

2: trifluoroacetic acid / 0.25 h / 120 °C / Microwave irradiation

With trifluoroacetic acid; hydrazine; In ethanol;