(Z)-2-(4-hydroxylphenyl)-1-[4-[2-(4-methylpiperazin-1-yl)ethoxy]phenyl]-1-phenylbut-1-ene

Base Information

Chemical Name:(Z)-2-(4-hydroxylphenyl)-1-[4-[2-(4-methylpiperazin-1-yl)ethoxy]phenyl]-1-phenylbut-1-ene
CAS No.:1276031-03-8
Molecular Formula:C₂₉H₃₄N₂O₂
Molecular Weight:442.601
Hs Code.:

Synonyms:(Z)-2-(4-hydroxylphenyl)-1-[4-[2-(4-methylpiperazin-1-yl)ethoxy]phenyl]-1-phenylbut-1-ene

Suppliers and Price of (Z)-2-(4-hydroxylphenyl)-1-[4-[2-(4-methylpiperazin-1-yl)ethoxy]phenyl]-1-phenylbut-1-ene

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (Z)-2-(4-hydroxylphenyl)-1-[4-[2-(4-methylpiperazin-1-yl)ethoxy]phenyl]-1-phenylbut-1-ene

Chemical Property:

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Technology Process of (Z)-2-(4-hydroxylphenyl)-1-[4-[2-(4-methylpiperazin-1-yl)ethoxy]phenyl]-1-phenylbut-1-ene

There total 3 articles about (Z)-2-(4-hydroxylphenyl)-1-[4-[2-(4-methylpiperazin-1-yl)ethoxy]phenyl]-1-phenylbut-1-ene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 109-01-3
1-methyl-piperazine

: 1276031-01-6
C₂₄H₂₃ClO₂

: 1276031-03-8
(Z)-2-(4-hydroxylphenyl)-1-[4-[2-(4-methylpiperazin-1-yl)ethoxy]phenyl]-1-phenylbut-1-ene

: 1307381-01-6
C₂₉H₃₄N₂O₂

Guidance literature:: In ethanol; for 24h; Reflux;
DOI:10.1016/j.bmcl.2010.12.091

Reference yield:

: 70-70-2
4-hydroxypropiophenone

: 1276031-03-8
(Z)-2-(4-hydroxylphenyl)-1-[4-[2-(4-methylpiperazin-1-yl)ethoxy]phenyl]-1-phenylbut-1-ene

Guidance literature:: Multi-step reaction with 2 steps

1: titanium tetrachloride; zinc / tetrahydrofuran / 0 °C / Inert atmosphere; Reflux

2: ethanol / 24 h / Reflux

With titanium tetrachloride; zinc; In tetrahydrofuran; ethanol; 1: McMurry reaction;
DOI:10.1016/j.bmcl.2010.12.091

Reference yield:

: 3439-73-4
4-(2-chloroethoxy)benzophenone

: 70-70-2
4-hydroxypropiophenone

: 1276031-03-8
(Z)-2-(4-hydroxylphenyl)-1-[4-[2-(4-methylpiperazin-1-yl)ethoxy]phenyl]-1-phenylbut-1-ene

: 1307381-01-6
C₂₉H₃₄N₂O₂

Guidance literature:: Multi-step reaction with 2 steps

1: titanium tetrachloride; zinc / tetrahydrofuran / 0 °C / Inert atmosphere; Reflux

2: ethanol / 24 h / Reflux

With titanium tetrachloride; zinc; In tetrahydrofuran; ethanol; 1: McMurry reaction;
DOI:10.1016/j.bmcl.2010.12.091