6-Oxo-1,6-dihydropyridazine-3-carbohydrazide

Base Information

• Chemical Name: 6-Oxo-1,6-dihydropyridazine-3-carbohydrazide
• CAS No.: 98021-39-7
• Molecular Formula: C5H6 N4 O2
• Molecular Weight: 154.128
• Hs Code.: 2933990090
• DSSTox Substance ID: DTXSID00365666
• Wikidata: Q82150514
• Mol file: 98021-39-7.mol

Synonyms:6-oxo-1,6-dihydropyridazine-3-carbohydrazide;98021-39-7;6-oxo-1H-pyridazine-3-carbohydrazide;6-Hydroxypyridazine-3-carbohydrazide;SCHEMBL24038943;DTXSID00365666;STK539319;AKOS005170705;CS-0222275;6-oxo-1,6-dihydro-3-pyridazinecarbohydrazide;EN300-110751

Chemical Property of 6-Oxo-1,6-dihydropyridazine-3-carbohydrazide

Chemical Property:

• Melting Point: 241 °C
• PKA: 9.17±0.20(Predicted)
• PSA: 101.13000
• Density: 1.71±0.1 g/cm3(Predicted)
• LogP: -0.12310
• XLogP3: -1.8
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 154.04907545
• Heavy Atom Count: 11
• Complexity: 255

Purity/Quality:

97% ^*data from raw suppliers

6-oxo-1,6-dihydropyridazine-3-carbohydrazide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=O)NN=C1C(=O)NN

Technology Process of 6-Oxo-1,6-dihydropyridazine-3-carbohydrazide

There total 3 articles about 6-Oxo-1,6-dihydropyridazine-3-carbohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.25%

methyl 6‐oxo‐1,6‐dihydropyridazine‐3‐carboxylate (63001-30-9) → 6-oxy-1,6-dihydropyridazine-3-carboxylic acid hydrazine (98021-39-7)

Guidance literature:

With hydrazine hydrate; In ethanol; at 40 ℃; for 3h;

Reference yield:

6-methoxypyridazine-3-carboxylic acid (56434-28-7) → 6-oxy-1,6-dihydropyridazine-3-carboxylic acid hydrazine (98021-39-7)

Guidance literature:

Multi-step reaction with 2 steps

1: sulfuric acid / methanol / 50 °C

2: hydrazine hydrate / ethanol / 3 h / 40 °C

With sulfuric acid; hydrazine hydrate; In methanol; ethanol;

Reference yield:

ethyl 1,6-dihydro-6-oxopyridazine-3-carboxylate (63001-31-0) → 6-oxy-1,6-dihydropyridazine-3-carboxylic acid hydrazine (98021-39-7)

Guidance literature:

With hydrazine hydrate;

upstream raw materials:

ethyl 1,6-dihydro-6-oxopyridazine-3-carboxylate

methyl 6‐oxo‐1,6‐dihydropyridazine‐3‐carboxylate

6-methoxypyridazine-3-carboxylic acid