Welcome to LookChem.com Sign In|Join Free

CAS

  • or

63001-31-0

Post Buying Request

63001-31-0 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

63001-31-0 Usage

Description

1,6-Dihydro-6-oxo-3-pyridazinecarboxylic acid, ethyl ester, an organic ester with the molecular formula C8H8N2O3, is the ethyl ester of 1,6-dihydro-6-oxo-3-pyridazinecarboxylic acid. It is a white crystalline solid with a melting point of approximately 80-82°C. This chemical compound is utilized in various applications across the chemical and pharmaceutical industries, including organic synthesis and as a building block for the production of pharmaceuticals and agrochemicals. Its potential medicinal properties also make it a valuable asset in research and development.

Uses

Used in Organic Synthesis:
1,6-Dihydro-6-oxo-3-pyridazinecarboxylic acid, ethyl ester is used as a key intermediate in organic synthesis for the production of various chemical compounds. Its unique structure allows for the formation of a wide range of derivatives, making it a versatile building block in the synthesis of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1,6-Dihydro-6-oxo-3-pyridazinecarboxylic acid, ethyl ester is used as a starting material for the synthesis of various drugs. Its presence in the molecular structure of certain pharmaceuticals contributes to their therapeutic effects, making it an essential component in drug development.
Used in Agrochemical Production:
1,6-Dihydro-6-oxo-3-pyridazinecarboxylic acid, ethyl ester is also utilized in the agrochemical industry for the synthesis of pesticides and other crop protection agents. Its incorporation into these products enhances their effectiveness in protecting crops from pests and diseases, thereby contributing to increased agricultural productivity.
Used in Research and Development:
Due to its potential medicinal properties, 1,6-Dihydro-6-oxo-3-pyridazinecarboxylic acid, ethyl ester is widely used in research and development for the discovery of new pharmaceuticals and agrochemicals. Its unique chemical structure provides a foundation for the exploration of novel therapeutic agents and innovative solutions in the fields of medicine and agriculture.

Check Digit Verification of cas no

The CAS Registry Mumber 63001-31-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,3,0,0 and 1 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 63001-31:
(7*6)+(6*3)+(5*0)+(4*0)+(3*1)+(2*3)+(1*1)=70
70 % 10 = 0
So 63001-31-0 is a valid CAS Registry Number.

63001-31-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name Ethyl 6-hydroxypyridazine-3-carboxylate

1.2 Other means of identification

Product number -
Other names 1,6-DIHYDRO-6-OXO-3-PYRIDAZINECARBOXYLIC ACID, ETHYL ESTER

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:63001-31-0 SDS

63001-31-0Relevant articles and documents

Developing pyridazine-3-carboxamides to be CB2 agonists: The design, synthesis, structure-activity relationships and docking studies

Qian, Hai-Yan,Wang, Zhi-Long,Xie, Xiao-Yu,Pan, You-Lu,Li, Gang-Jian,Xie, Xin,Chen, Jian-Zhong

, p. 598 - 611 (2017/06/29)

Herein, we described the design and synthesis of a series of pyridazine-3-carboxamides to be CB2-selective agonists via a combination of scaffold hopping and bioisosterism strategies. The compounds were subjected to assessment of their potential activities through calcium mobilization assays. Among the tested derivatives, more than half of these compounds exhibited moderate to potent CB2 agonist activity. Six compounds showed EC50 values below 35 nM, and several derivatives also exhibited significantly enhanced potency and high selectivity at the CB2 receptor over the CB1 receptor. Specifically, compound 26 showed the highest CB2 agonist activity (EC50 = 3.665 ± 0.553 nM) and remarkable selectivity (Selectivity Index > 2729) against CB1. In addition, logPs of some representative compounds were measured to display significantly decreased values in comparison with GW842166X. Furthermore, docking simulations were conducted to explain the interaction mode of this series.

A novel method for the synthesis of 3,4-disubstitutedpyrrole-2,5- dicarboxylates from hydrazones derived from α-diazo esters

Yasui, Eiko,Wada, Masao,Nagumo, Shinji,Takamura, Norio

, p. 4325 - 4330 (2013/06/27)

Hydrazones obtained from α-diazo esters were converted to pyrroles when heated with thionyl chloride in alcohol. Among hydrazones, those substituted with a benzene ring on the β-carbon to the ester are likely to give pyrroles in good yields.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 63001-31-0