N-[3-(N-tert-butoxycarbonyl-hydrazino)-phenyl]-hydrazinecarboxylic acid tert-butyl ester

Base Information

• Chemical Name: N-[3-(N-tert-butoxycarbonyl-hydrazino)-phenyl]-hydrazinecarboxylic acid tert-butyl ester
• CAS No.: 890041-18-6
• Molecular Formula: C₁₆H₂₆N₄O₄
• Molecular Weight: 338.407
• Mol file: 890041-18-6.mol

Synonyms:N-[3-(N-tert-butoxycarbonyl-hydrazino)-phenyl]-hydrazinecarboxylic acid tert-butyl ester

Chemical Property of N-[3-(N-tert-butoxycarbonyl-hydrazino)-phenyl]-hydrazinecarboxylic acid tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of N-[3-(N-tert-butoxycarbonyl-hydrazino)-phenyl]-hydrazinecarboxylic acid tert-butyl ester

There total 1 articles about N-[3-(N-tert-butoxycarbonyl-hydrazino)-phenyl]-hydrazinecarboxylic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 82.0%

t-butoxycarbonylhydrazine (870-46-2) + 1,3-Diiodobenzene (626-00-6) → N-[3-(N-tert-butoxycarbonyl-hydrazino)-phenyl]-hydrazinecarboxylic acid tert-butyl ester (890041-18-6)

Guidance literature:

With copper(l) iodide; 1,10-Phenanthroline; caesium carbonate; In N,N-dimethyl-formamide; at 80 ℃; for 6h;

DOI:10.1021/ol060451+

Reference yield: 75.0%

N-[3-(N-tert-butoxycarbonyl-hydrazino)-phenyl]-hydrazinecarboxylic acid tert-butyl ester (890041-18-6) + 1-butyloxy-3,5-dichloro-2,4,6-triazine (13838-32-9) → C30H42Cl2N10O6

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 0 - 20 ℃; for 4h;

DOI:10.1021/acs.joc.8b00284

Reference yield: 64.0%

N-[3-(N-tert-butoxycarbonyl-hydrazino)-phenyl]-hydrazinecarboxylic acid tert-butyl ester (890041-18-6) + o-iodo-methyl-benzoic acid (610-97-9) → di-tert-butyl 1,1'-(1,3-phenylene)bis(2-(2-(methoxycarbonyl)phenyl)hydrazinecarboxylate)

Guidance literature:

With palladium diacetate; caesium carbonate; tri tert-butylphosphoniumtetrafluoroborate; In toluene; for 2h; Heating;

DOI:10.1021/ol060451+

upstream raw materials:

t-butoxycarbonylhydrazine

1,3-Diiodobenzene

Downstream raw materials:

di-tert-butyl 1,1'-(1,3-phenylene)bis(2-phenylhydrazinecarboxylate)

di-tert-butyl 1,1'-(1,3-phenylene)bis(2-o-tolylhydrazinecarboxylate)

di-tert-butyl 1,1'-(1,3-phenylene)bis(2-(2,6-dimethylphenyl)hydrazinecarboxylate)