di-tert-butyl 1,1'-(1,3-phenylene)bis(2-(2,6-dimethylphenyl)hydrazinecarboxylate)

Base Information

• Chemical Name: di-tert-butyl 1,1'-(1,3-phenylene)bis(2-(2,6-dimethylphenyl)hydrazinecarboxylate)
• CAS No.: 890041-22-2
• Molecular Formula: C₃₂H₄₂N₄O₄
• Molecular Weight: 546.71
• Mol file: 890041-22-2.mol

Synonyms:di-tert-butyl 1,1'-(1,3-phenylene)bis(2-(2,6-dimethylphenyl)hydrazinecarboxylate)

Chemical Property of di-tert-butyl 1,1'-(1,3-phenylene)bis(2-(2,6-dimethylphenyl)hydrazinecarboxylate)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of di-tert-butyl 1,1'-(1,3-phenylene)bis(2-(2,6-dimethylphenyl)hydrazinecarboxylate)

There total 3 articles about di-tert-butyl 1,1'-(1,3-phenylene)bis(2-(2,6-dimethylphenyl)hydrazinecarboxylate) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

N-[3-(N-tert-butoxycarbonyl-hydrazino)-phenyl]-hydrazinecarboxylic acid tert-butyl ester (890041-18-6) + 2,6-dimethyliodobenzene (608-28-6) → di-tert-butyl 1,1'-(1,3-phenylene)bis(2-(2,6-dimethylphenyl)hydrazinecarboxylate) (890041-22-2)

Guidance literature:

With palladium diacetate; caesium carbonate; tri tert-butylphosphoniumtetrafluoroborate; In toluene; for 2h; Heating;

DOI:10.1021/ol060451+

Reference yield:

t-butoxycarbonylhydrazine (870-46-2) → di-tert-butyl 1,1'-(1,3-phenylene)bis(2-(2,6-dimethylphenyl)hydrazinecarboxylate) (890041-22-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 82 percent / CuI; 1,10-phenanthroline; Cs₂CO₃ / dimethylformamide / 6 h / 80 °C

2: 57 percent / P(t-Bu)3*HBF₄; Cs₂CO₃; Pd(OAc)2 / toluene / 2 h / Heating

With palladium diacetate; copper(l) iodide; 1,10-Phenanthroline; caesium carbonate; tri tert-butylphosphoniumtetrafluoroborate; In N,N-dimethyl-formamide; toluene;

DOI:10.1021/ol060451+

Reference yield:

1,3-Diiodobenzene (626-00-6) → di-tert-butyl 1,1'-(1,3-phenylene)bis(2-(2,6-dimethylphenyl)hydrazinecarboxylate) (890041-22-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 82 percent / CuI; 1,10-phenanthroline; Cs₂CO₃ / dimethylformamide / 6 h / 80 °C

2: 57 percent / P(t-Bu)3*HBF₄; Cs₂CO₃; Pd(OAc)2 / toluene / 2 h / Heating

With palladium diacetate; copper(l) iodide; 1,10-Phenanthroline; caesium carbonate; tri tert-butylphosphoniumtetrafluoroborate; In N,N-dimethyl-formamide; toluene;

DOI:10.1021/ol060451+

upstream raw materials:

N-[3-(N-tert-butoxycarbonyl-hydrazino)-phenyl]-hydrazinecarboxylic acid tert-butyl ester

2,6-dimethyliodobenzene

t-butoxycarbonylhydrazine

1,3-Diiodobenzene