4,8,12,16-tetra(p-toluenesulfonyl)-4,8,12,16-tetraazaundecane-1,19-diamine

Base Information

• Chemical Name: 4,8,12,16-tetra(p-toluenesulfonyl)-4,8,12,16-tetraazaundecane-1,19-diamine
• CAS No.: 87265-95-0
• Molecular Formula: C₄₃H₆₂N₆O₈S₄
• Molecular Weight: 919.265
• Mol file: 87265-95-0.mol

Synonyms:4,8,12,16-tetra(p-toluenesulfonyl)-4,8,12,16-tetraazaundecane-1,19-diamine

Chemical Property of 4,8,12,16-tetra(p-toluenesulfonyl)-4,8,12,16-tetraazaundecane-1,19-diamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,8,12,16-tetra(p-toluenesulfonyl)-4,8,12,16-tetraazaundecane-1,19-diamine

There total 10 articles about 4,8,12,16-tetra(p-toluenesulfonyl)-4,8,12,16-tetraazaundecane-1,19-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1,21-phthalimido-5,9,13,17-tetrakis(p-tolylsulfonyl)-1,5,9,13,17,21-hexaazahenicosane (916444-04-7) → 4,8,12,16-tetra(p-toluenesulfonyl)-4,8,12,16-tetraazaundecane-1,19-diamine (87265-95-0)

Guidance literature:

With hydrazine hydrate; In tetrahydrofuran; for 12h; Heating;

DOI:10.1039/b611031b

Reference yield: 76.0%

1,21-phthalimido-5,9,13,17-tetrakis(p-tolylsulfonyl)-1,5,9,13,17,21-hexaazahenicosane (916444-04-7) + hydrazine hydrate (7803-57-8,79785-97-0) → 4,8,12,16-tetra(p-toluenesulfonyl)-4,8,12,16-tetraazaundecane-1,19-diamine (87265-95-0)

Guidance literature:

In tetrahydrofuran; for 24h; Reflux;

DOI:10.1039/c3dt51012c

Reference yield:

N,N'-bis<3-(tosylamino)propyl>-N,N'-ditosyl-1,3-propanediamine (67341-38-2) → 4,8,12,16-tetra(p-toluenesulfonyl)-4,8,12,16-tetraazaundecane-1,19-diamine (87265-95-0)

Guidance literature:

Multi-step reaction with 2 steps

1: 98 percent / K₂CO₃ / acetonitrile / 12 h / Heating

2: 99 percent / hydrazine monohydrate / tetrahydrofuran / 12 h / Heating

With potassium carbonate; hydrazine hydrate; In tetrahydrofuran; acetonitrile;

DOI:10.1039/b611031b

upstream raw materials:

4,8,12,16-tetra(p-toluenesulfonyl)-4,8,12,16-tetraazaundecanedinitrile

1,21-phthalimido-5,9,13,17-tetrakis(p-tolylsulfonyl)-1,5,9,13,17,21-hexaazahenicosane

N,N'-bis<3-(tosylamino)propyl>-N,N'-ditosyl-1,3-propanediamine

N,N'-ditoluenesulfonyl-1,3-diaminopropane

Downstream raw materials:

N,N',4,8,12,16-hexa(p-toluenesulfonyl)-4,8,12,16-tetraazaundecane-1,19-diamine