(2S,3aS,7aS)-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid methyl ester hydrochloride

Base Information

• Chemical Name: (2S,3aS,7aS)-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid methyl ester hydrochloride
• CAS No.: 781676-62-8
• Molecular Formula: C₁₀H₁₇NO₂*ClH
• Molecular Weight: 219.711
• Mol file: 781676-62-8.mol

Synonyms:(2S,3aS,7aS)-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid methyl ester hydrochloride

Chemical Property of (2S,3aS,7aS)-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid methyl ester hydrochloride

Chemical Property:

Purity/Quality:

95%+ or 98%+ ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2S,3aS,7aS)-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid methyl ester hydrochloride

There total 2 articles about (2S,3aS,7aS)-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid methyl ester hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(2S,3aS,7aS)-perhydroindole-2-carboxylic acid (80875-98-5,2055118-14-2) → (2S,3aS,7aS)-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid methyl ester hydrochloride (781676-62-8,195878-03-6)

Guidance literature:

With hydrogenchloride; In methanol; at 20 ℃; for 48h;

Reference yield:

methanol (67-56-1) + (2S,3aS,7aS)-perhydroindole-2-carboxylic acid (80875-98-5,2055118-14-2) → (2S,3aS,7aS)-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid methyl ester hydrochloride (781676-62-8,195878-03-6)

Guidance literature:

With chloro-trimethyl-silane; at 20 ℃; for 15h;

DOI:10.1002/psc.3076

Reference yield:

(2S,3aS,7aS)-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid methyl ester hydrochloride (781676-62-8,195878-03-6) + trityl chloride (76-83-5) → C29H31NO2

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 16h;

upstream raw materials:

(2S,3aS,7aS)-perhydroindole-2-carboxylic acid

methanol