3-<2-hydroxy-3-(5-methyl-4-phenyl-1H-imidazol-1-yl)propoxy>-2-nitrotoluene

Base Information

Chemical Name:3-<2-hydroxy-3-(5-methyl-4-phenyl-1H-imidazol-1-yl)propoxy>-2-nitrotoluene
CAS No.:148726-36-7
Molecular Formula:C₂₀H₂₁N₃O₄
Molecular Weight:367.404
Hs Code.:

Synonyms:3-<2-hydroxy-3-(5-methyl-4-phenyl-1H-imidazol-1-yl)propoxy>-2-nitrotoluene

Suppliers and Price of 3-<2-hydroxy-3-(5-methyl-4-phenyl-1H-imidazol-1-yl)propoxy>-2-nitrotoluene

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-<2-hydroxy-3-(5-methyl-4-phenyl-1H-imidazol-1-yl)propoxy>-2-nitrotoluene

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Technology Process of 3-<2-hydroxy-3-(5-methyl-4-phenyl-1H-imidazol-1-yl)propoxy>-2-nitrotoluene

There total 2 articles about 3-<2-hydroxy-3-(5-methyl-4-phenyl-1H-imidazol-1-yl)propoxy>-2-nitrotoluene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4920-77-8
3-methyl-2-nitrophenol

: 148726-36-7
3-<2-hydroxy-3-(5-methyl-4-phenyl-1H-imidazol-1-yl)propoxy>-2-nitrotoluene

Guidance literature:: Multi-step reaction with 2 steps

1: K₂CO₃ / tetrahydrofuran; dimethylformamide / 2 h / Ambient temperature

2: 1.) NaH / 1.) DMF, 60 deg C, 1 h, 2.) DMF, 60 deg C, 2 h

With sodium hydride; potassium carbonate; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/jm00063a014

Reference yield:

: 826-83-5
4(5)-phenyl-5(4)-methylimidazole

: 67823-49-8
2-(3-Methyl-2-nitro-phenoxymethyl)-oxirane

: 148726-36-7
3-<2-hydroxy-3-(5-methyl-4-phenyl-1H-imidazol-1-yl)propoxy>-2-nitrotoluene

Guidance literature:: With sodium hydride; Yield given. Multistep reaction; 1.) DMF, 60 deg C, 1 h, 2.) DMF, 60 deg C, 2 h;
DOI:10.1021/jm00063a014