(S)-(+)-(N-(S)-p-toluenesulfinyl)-2-amino-5,5-(ethylednedioxy)-5-phenylhexanonitrile

Base Information

Chemical Name:(S)-(+)-(N-(S)-p-toluenesulfinyl)-2-amino-5,5-(ethylednedioxy)-5-phenylhexanonitrile
CAS No.:332072-79-4
Molecular Formula:C₂₁H₂₄N₂O₃S
Molecular Weight:384.499
Hs Code.:

Synonyms:(S)-(+)-(N-(S)-p-toluenesulfinyl)-2-amino-5,5-(ethylednedioxy)-5-phenylhexanonitrile

Suppliers and Price of (S)-(+)-(N-(S)-p-toluenesulfinyl)-2-amino-5,5-(ethylednedioxy)-5-phenylhexanonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-(+)-(N-(S)-p-toluenesulfinyl)-2-amino-5,5-(ethylednedioxy)-5-phenylhexanonitrile

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-(+)-(N-(S)-p-toluenesulfinyl)-2-amino-5,5-(ethylednedioxy)-5-phenylhexanonitrile

There total 3 articles about (S)-(+)-(N-(S)-p-toluenesulfinyl)-2-amino-5,5-(ethylednedioxy)-5-phenylhexanonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 5804-85-3
diethylaluminium cyanide

: 332072-74-9
(S)-(+)-N-[5,5-(ethylenedioxy)-5-phenyl-pentanylidene]-p-toluenesulfinamide

: 4-Methyl-benzenesulfinic acid [(R)-1-cyano-4-(2-phenyl-[1,3]dioxolan-2-yl)-butyl]-amide

: 332072-79-4
(S)-(+)-(N-(S)-p-toluenesulfinyl)-2-amino-5,5-(ethylednedioxy)-5-phenylhexanonitrile

Guidance literature:: With isopropyl alcohol; In tetrahydrofuran; at -78 ℃;
DOI:10.1021/ol015520t

Reference yield:

: 17851-44-4
ethyl 6-phenyl 5,5-(ethylenedioxy)hexanoate

: 332072-79-4
(S)-(+)-(N-(S)-p-toluenesulfinyl)-2-amino-5,5-(ethylednedioxy)-5-phenylhexanonitrile

Guidance literature:: Multi-step reaction with 3 steps

1.1: 65 percent / diisobutylaluminum hydride / CH₂Cl₂ / -78 °C

2.1: 80 percent / titanium (IV) ethoxide / CH₂Cl₂ / 0.5 h / 20 °C

3.1: i-PrOH / tetrahydrofuran / 20 °C

3.2: 90 percent / tetrahydrofuran / -78 - 20 °C

With titanium(IV) tetraethanolate; diisobutylaluminium hydride; isopropyl alcohol; In tetrahydrofuran; dichloromethane;
DOI:10.1021/ol015520t

Reference yield:

: 165613-10-5
5,5-(ethylenedioxy)-5-phenylpentanal

: 332072-79-4
(S)-(+)-(N-(S)-p-toluenesulfinyl)-2-amino-5,5-(ethylednedioxy)-5-phenylhexanonitrile

Guidance literature:: Multi-step reaction with 2 steps

1.1: 80 percent / titanium (IV) ethoxide / CH₂Cl₂ / 0.5 h / 20 °C

2.1: i-PrOH / tetrahydrofuran / 20 °C

2.2: 90 percent / tetrahydrofuran / -78 - 20 °C

With titanium(IV) tetraethanolate; isopropyl alcohol; In tetrahydrofuran; dichloromethane;
DOI:10.1021/ol015520t