tert-Butyl(4-iodobutoxy)dimethylsilane

Base Information

• Chemical Name: tert-Butyl(4-iodobutoxy)dimethylsilane
• CAS No.: 92511-12-1
• Molecular Formula: C10H23IOSi
• Molecular Weight: 314.282
• Hs Code.: 2931900090
• European Community (EC) Number: 861-295-7
• DSSTox Substance ID: DTXSID30401223
• Nikkaji Number: J428.960I
• Wikidata: Q82204287
• Mol file: 92511-12-1.mol

Synonyms:tert-Butyl(4-iodobutoxy)dimethylsilane;92511-12-1;tert-butyl-(4-iodobutoxy)-dimethylsilane;(4-Iodobutoxy)-t-butyldimethylsilane;MFCD01863695;1-(tert-Butyldimethylsilyloxy)-4-iodobutane;C10H23IOSi;TERT-BUTYL-(4-IODO-BUTOXY)-DIMETHYL-SILANE;SCHEMBL345800;Silane, (1,1-dimethylethyl)(4-iodobutoxy)dimethyl-;DTXSID30401223;INGJYKISFRSCQV-UHFFFAOYSA-N;AMY42269;AKOS028111859;(4-iodobutoxy)-tert-butyldimethylsilane;4-(t-butyldimethylsilyloxy)-1-iodobutane;AS-49499;SY120633;(4-iodo-butoxy)-tert-butyl-dimethyl-silane;CS-0134269;FT-0751228;tert-Butyl(4-iodobutoxy)dimethylsilane, 95%;I10999;EN300-7394987;A860060

Chemical Property of tert-Butyl(4-iodobutoxy)dimethylsilane

Chemical Property:

• Vapor Pressure: 0.0297mmHg at 25°C
• Refractive Index: n20/D 1.48(lit.)
• Boiling Point: 253.1 °C at 760 mmHg
• Flash Point: 106.8 °C
• PSA: 9.23000
• Density: 1.234 g/cm³
• LogP: 4.22340
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 6
• Exact Mass: 314.05629
• Heavy Atom Count: 13
• Complexity: 140

Purity/Quality:

97% ^*data from raw suppliers

tert-Butyl(4-iodobutoxy)dimethylsilane ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)(C)[Si](C)(C)OCCCCI
• Uses: tert-Butyl(4-iodobutoxy)dimethylsilane may be used as a reagent in the multi-step synthesis of spermine synthon and decanucleotide-spermine conjugates.

Technology Process of tert-Butyl(4-iodobutoxy)dimethylsilane

There total 7 articles about tert-Butyl(4-iodobutoxy)dimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

tetrahydrofuran (109-99-9,24979-97-3,77392-70-2) + tert-butyldimethylsilyl chloride (18162-48-6) → 1-{[dimethyl(1,1-dimethylethyl)silyl]oxy}-4-iodobutane (92511-12-1)

Guidance literature:

With sodium iodide; In acetonitrile; at 55 ℃; for 16h; Inert atmosphere;

DOI:10.1002/adsc.200800154

Reference yield: 98.0%

4-tert-butyldimethylsilyloxybutan-1-ol (87184-99-4) → 1-{[dimethyl(1,1-dimethylethyl)silyl]oxy}-4-iodobutane (92511-12-1)

Guidance literature:

With 1H-imidazole; iodine; triphenylphosphine; In toluene; acetonitrile; at 20 ℃; for 0.5h;

DOI:10.24820/ark.5550190.p010.939

Reference yield: 81.0%

4-<(tert-butyldimethylsiloxy)oxy>butyl p-toluenesulfonate (136160-47-9) → 1-{[dimethyl(1,1-dimethylethyl)silyl]oxy}-4-iodobutane (92511-12-1)

Guidance literature:

With sodium iodide; In acetone; for 16h; Heating;

DOI:10.1021/ja00087a021

upstream raw materials:

tetrahydrofuran

tert-butyldimethylsilyl chloride

4-tert-butyldimethylsilyloxybutan-1-ol

4-iodo-butan-1-ol

Downstream raw materials:

Acetic acid 5-(tert-butyl-dimethyl-silanyloxy)-1-cyclohex-1-enyl-pentyl ester

N-benzyl-4-((tert-butyldimethylsilyl)oxy)butan-1-amine

7-{[tert-butyl(dimethyl)silyl]oxy}-1-phenylhept-1-yn-3-one

tert-butyl-(6-cyclohexylhex-5-ynyloxy)dimethylsilane