ethyl (2E,4Z)-5-[4-(oxetan-3-yloxy)phenyl]-5-(4-trifluoromethylphenyl)-2,4-pentadienoate

Base Information

Chemical Name:ethyl (2E,4Z)-5-[4-(oxetan-3-yloxy)phenyl]-5-(4-trifluoromethylphenyl)-2,4-pentadienoate
CAS No.:1369534-98-4
Molecular Formula:C₂₃H₂₁F₃O₄
Molecular Weight:418.413
Hs Code.:

Synonyms:ethyl (2E,4Z)-5-[4-(oxetan-3-yloxy)phenyl]-5-(4-trifluoromethylphenyl)-2,4-pentadienoate

Suppliers and Price of ethyl (2E,4Z)-5-[4-(oxetan-3-yloxy)phenyl]-5-(4-trifluoromethylphenyl)-2,4-pentadienoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of ethyl (2E,4Z)-5-[4-(oxetan-3-yloxy)phenyl]-5-(4-trifluoromethylphenyl)-2,4-pentadienoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of ethyl (2E,4Z)-5-[4-(oxetan-3-yloxy)phenyl]-5-(4-trifluoromethylphenyl)-2,4-pentadienoate

There total 6 articles about ethyl (2E,4Z)-5-[4-(oxetan-3-yloxy)phenyl]-5-(4-trifluoromethylphenyl)-2,4-pentadienoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 1369534-96-2
3-(4-bromophenoxy)oxetane

: 1369534-97-3
ethyl (2E,4E)-5-(4,4,5,5-tetramethyl[1,3,2]dioxaborolan-2-yl)-5-(4-trifluoromethylphenyl)-2,4-pentadienoate

: 1369534-98-4
ethyl (2E,4Z)-5-[4-(oxetan-3-yloxy)phenyl]-5-(4-trifluoromethylphenyl)-2,4-pentadienoate

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In tetrahydrofuran; water; at 70 ℃; for 6h; Inert atmosphere;
DOI:10.1021/jm300101n

Reference yield:

: 1369534-95-1
2-(4-bromophenoxy)-3-tosyloxy-1-propanol

: 1369534-98-4
ethyl (2E,4Z)-5-[4-(oxetan-3-yloxy)phenyl]-5-(4-trifluoromethylphenyl)-2,4-pentadienoate

Guidance literature:: Multi-step reaction with 2 steps

1: sodium hydride / tetrahydrofuran; mineral oil / 23 h / 0 - 40 °C

2: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / tetrahydrofuran; water / 6 h / 70 °C / Inert atmosphere

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydride; sodium carbonate; In tetrahydrofuran; water; mineral oil;
DOI:10.1021/jm300101n

Reference yield:

: 1369534-94-0
2-(4-bromophenoxy)-1,3-diacetoxypropane

: 1369534-98-4
ethyl (2E,4Z)-5-[4-(oxetan-3-yloxy)phenyl]-5-(4-trifluoromethylphenyl)-2,4-pentadienoate

Guidance literature:: Multi-step reaction with 4 steps

1: water; lithium hydroxide / tetrahydrofuran; methanol / 28 h / 20 °C / Inert atmosphere

2: sodium hydride / tetrahydrofuran; mineral oil / 0.17 h / 0 °C / Inert atmosphere

3: sodium hydride / tetrahydrofuran; mineral oil / 23 h / 0 - 40 °C

4: tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate / tetrahydrofuran; water / 6 h / 70 °C / Inert atmosphere

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; water; sodium hydride; sodium carbonate; lithium hydroxide; In tetrahydrofuran; methanol; water; mineral oil;
DOI:10.1021/jm300101n