Technology Process of 2-(4-bromophenoxy)-1,3-diacetoxypropane
There total 1 articles about 2-(4-bromophenoxy)-1,3-diacetoxypropane which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
triphenylphosphine; diethylazodicarboxylate;
In
toluene;
at 20 ℃;
for 5.5h;
Inert atmosphere;
DOI:10.1021/jm300101n
- Guidance literature:
-
With
water; lithium hydroxide;
In
tetrahydrofuran; methanol;
at 20 ℃;
for 28h;
Inert atmosphere;
DOI:10.1021/jm300101n
- Guidance literature:
-
Multi-step reaction with 5 steps
1: water; lithium hydroxide / tetrahydrofuran; methanol / 28 h / 20 °C / Inert atmosphere
2: sodium hydride / tetrahydrofuran; mineral oil / 0.17 h / 0 °C / Inert atmosphere
3: sodium hydride / tetrahydrofuran; mineral oil / 23 h / 0 - 40 °C
4: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / tetrahydrofuran; water / 6 h / 70 °C / Inert atmosphere
5: water; lithium hydroxide / tetrahydrofuran; methanol / 20 °C / Inert atmosphere
With
tetrakis(triphenylphosphine) palladium(0); water; sodium hydride; sodium carbonate; lithium hydroxide;
In
tetrahydrofuran; methanol; water; mineral oil;
DOI:10.1021/jm300101n
