(4-(2-fluoro-4-(3-methyl-[1,2,4]oxadiazol-5-yl)phenyl)piperazin-1-yl)phenylacetic acid ethyl ester

Base Information

Chemical Name:(4-(2-fluoro-4-(3-methyl-[1,2,4]oxadiazol-5-yl)phenyl)piperazin-1-yl)phenylacetic acid ethyl ester
CAS No.:1163246-90-9
Molecular Formula:C₂₃H₂₅FN₄O₃
Molecular Weight:424.475
Hs Code.:

Synonyms:(4-(2-fluoro-4-(3-methyl-[1,2,4]oxadiazol-5-yl)phenyl)piperazin-1-yl)phenylacetic acid ethyl ester

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Chemical Property of (4-(2-fluoro-4-(3-methyl-[1,2,4]oxadiazol-5-yl)phenyl)piperazin-1-yl)phenylacetic acid ethyl ester

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Technology Process of (4-(2-fluoro-4-(3-methyl-[1,2,4]oxadiazol-5-yl)phenyl)piperazin-1-yl)phenylacetic acid ethyl ester

There total 1 articles about (4-(2-fluoro-4-(3-methyl-[1,2,4]oxadiazol-5-yl)phenyl)piperazin-1-yl)phenylacetic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1163247-92-4
1-(2-fluoro-4-(3-methyl-[1,2,4]oxadiazol-5-yl)phenyl)piperazine

: 2882-19-1,2216-90-2
ethyl 2-phenyl-2-bromoacetate

: 1163246-90-9
(4-(2-fluoro-4-(3-methyl-[1,2,4]oxadiazol-5-yl)phenyl)piperazin-1-yl)phenylacetic acid ethyl ester

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; for 16h;

Reference yield:

: 1163246-90-9
(4-(2-fluoro-4-(3-methyl-[1,2,4]oxadiazol-5-yl)phenyl)piperazin-1-yl)phenylacetic acid ethyl ester

: 74-88-4
methyl iodide

: 1163246-96-5
2-(4-(2-fluoro-4-(3-methyl-[1,2,4]oxadiazol-5-yl)phenyl)piperazin-1-yl)-2-phenylpropionic acid ethyl ester

Guidance literature:: (4-(2-fluoro-4-(3-methyl-[1,2,4]oxadiazol-5-yl)phenyl)piperazin-1-yl)phenylacetic acid ethyl ester; With sodium hexamethyldisilazane; In tetrahydrofuran; at -78 ℃; for 1h;

methyl iodide; In tetrahydrofuran; at -78 - 20 ℃; for 3h;