N′-(2-hydroxy-3-methoxybenzylidene)-2-hydroxybenzoylhydrazide

Base Information

• Chemical Name: N′-(2-hydroxy-3-methoxybenzylidene)-2-hydroxybenzoylhydrazide
• CAS No.: 115695-42-6
• Molecular Formula: C₁₅H₁₄N₂O₄
• Molecular Weight: 286.287
• Mol file: 115695-42-6.mol

Synonyms:N′-(2-hydroxy-3-methoxybenzylidene)-2-hydroxybenzoylhydrazide

Chemical Property of N′-(2-hydroxy-3-methoxybenzylidene)-2-hydroxybenzoylhydrazide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of N′-(2-hydroxy-3-methoxybenzylidene)-2-hydroxybenzoylhydrazide

There total 4 articles about N′-(2-hydroxy-3-methoxybenzylidene)-2-hydroxybenzoylhydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

3-methoxy-2-hydroxybenzaldehyde (148-53-8) + 2-Hydroxybenzoylhydrazine (936-02-7) → N′-(2-hydroxy-3-methoxybenzylidene)-2-hydroxybenzoylhydrazide (115695-42-6)

Guidance literature:

In methanol; for 2h; Reflux;

DOI:10.1080/00958972.2012.731049

Reference yield: 89.0%

salicylaldehyde (90-02-8) + 2-Hydroxybenzoylhydrazine (936-02-7) → N′-(2-hydroxy-3-methoxybenzylidene)-2-hydroxybenzoylhydrazide (115695-42-6)

Guidance literature:

In ethanol; for 6h; Reflux;

DOI:10.1016/j.jinorgbio.2015.05.013

Reference yield:

methyl salicylate (119-36-8,8024-54-2) → N′-(2-hydroxy-3-methoxybenzylidene)-2-hydroxybenzoylhydrazide (115695-42-6)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrazine / ethanol / Reflux

2: ethanol / 0.6 h / 78 °C

With hydrazine; In ethanol;

DOI:10.1002/cjoc.201800115

upstream raw materials:

3-methoxy-2-hydroxybenzaldehyde

2-Hydroxybenzoylhydrazine

salicylaldehyde

methyl salicylate