4-nitrophenyl O-(5-acetamido-3,5-dideoxy-α-D-glycero-D-galacto-2-nonulopyranosylonic acid)-(2->3)-β-D-galactopyranoside

Base Information

• Chemical Name: 4-nitrophenyl O-(5-acetamido-3,5-dideoxy-α-D-glycero-D-galacto-2-nonulopyranosylonic acid)-(2->3)-β-D-galactopyranoside
• CAS No.: 81123-28-6
• Molecular Formula: C₂₃H₃₂N₂O₁₆
• Molecular Weight: 592.511
• Mol file: 81123-28-6.mol

Synonyms:4-nitrophenyl O-(5-acetamido-3,5-dideoxy-α-D-glycero-D-galacto-2-nonulopyranosylonic acid)-(2->3)-β-D-galactopyranoside

Chemical Property of 4-nitrophenyl O-(5-acetamido-3,5-dideoxy-α-D-glycero-D-galacto-2-nonulopyranosylonic acid)-(2->3)-β-D-galactopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-nitrophenyl O-(5-acetamido-3,5-dideoxy-α-D-glycero-D-galacto-2-nonulopyranosylonic acid)-(2->3)-β-D-galactopyranoside

There total 2 articles about 4-nitrophenyl O-(5-acetamido-3,5-dideoxy-α-D-glycero-D-galacto-2-nonulopyranosylonic acid)-(2->3)-β-D-galactopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

N-acetyl neuraminic acid (6813-81-6,14120-72-0,19342-33-7,21646-00-4,82349-00-6,99395-98-9,99395-99-0,99396-00-6,102734-10-1,489-46-3,140671-47-2,140850-42-6,140850-43-7,140850-44-8,145375-13-9) + 4-nitrophenyl-β-D-galactopyranoside (3150-24-1) → 4-nitrophenyl O-(5-acetamido-3,5-dideoxy-α-D-glycero-D-galacto-2-nonulopyranosylonic acid)-(2->3)-β-D-galactopyranoside (81123-28-6)

Guidance literature:

With Neisseria meningitidis cytidine 5'-monophosphate-sialic acid synthetase; Pasteurella multocida α2-3-sialyltransferase M144D mutant; cytidine triphosphate; magnesium chloride; In aq. buffer; for 48h; pH=8; Enzymatic reaction;

DOI:10.1039/c6ob02240e

Reference yield: 42.0%

cytidine 5'-monophosphate-N-acetylneuraminic acid (55569-66-9) + 4-nitrophenyl-β-D-galactopyranoside (3150-24-1) → 4-nitrophenyl O-(5-acetamido-3,5-dideoxy-α-D-glycero-D-galacto-2-nonulopyranosylonic acid)-(2->3)-β-D-galactopyranoside (81123-28-6)

Guidance literature:

With sodium cacodylate buffer; at 37 ℃; for 52h; bovine serum albumin, alkaline phosphatase, β-D-galactoside α(2->6)-sialyltransferase;

DOI:10.1016/0008-6215(91)84090-2

Reference yield: 95.0%

sodium pyruvate (113-24-6) + 2-azido-2-deoxy-D-mannopyranose (97604-58-5) + 4-nitrophenyl O-(5-acetamido-3,5-dideoxy-α-D-glycero-D-galacto-2-nonulopyranosylonic acid)-(2->3)-β-D-galactopyranoside (81123-28-6) → C32H45N5O23

Guidance literature:

With Pasteurella multocida sialic acid aldolase; Campylobacter jejuni α2-3/8-sialyltransferase; Neisseria meningitidis cytidine 5'-monophosphate-sialic acid synthetase; cytidine triphosphate; magnesium chloride; In aq. buffer; at 20 ℃; for 4h; pH=8; Enzymatic reaction;

DOI:10.1039/c6ob02240e

upstream raw materials:

cytidine 5'-monophosphate-N-acetylneuraminic acid

4-nitrophenyl-β-D-galactopyranoside

N-acetyl neuraminic acid