N-(2-(4-bromo-1H-indol-3-yl)ethyl)-N-(4-methoxybenzyl)-3-(triisopropylsilyl)propiolamide

Base Information

Chemical Name:N-(2-(4-bromo-1H-indol-3-yl)ethyl)-N-(4-methoxybenzyl)-3-(triisopropylsilyl)propiolamide
CAS No.:1294437-54-9
Molecular Formula:C₃₀H₃₉BrN₂O₂Si
Molecular Weight:567.641
Hs Code.:

Synonyms:N-(2-(4-bromo-1H-indol-3-yl)ethyl)-N-(4-methoxybenzyl)-3-(triisopropylsilyl)propiolamide

Suppliers and Price of N-(2-(4-bromo-1H-indol-3-yl)ethyl)-N-(4-methoxybenzyl)-3-(triisopropylsilyl)propiolamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of N-(2-(4-bromo-1H-indol-3-yl)ethyl)-N-(4-methoxybenzyl)-3-(triisopropylsilyl)propiolamide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of N-(2-(4-bromo-1H-indol-3-yl)ethyl)-N-(4-methoxybenzyl)-3-(triisopropylsilyl)propiolamide

There total 4 articles about N-(2-(4-bromo-1H-indol-3-yl)ethyl)-N-(4-methoxybenzyl)-3-(triisopropylsilyl)propiolamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 1294437-40-3
2-(4-bromo-1H-indol-3-yl)-N-(4-methoxybenzyl)ethanamine

: 839697-82-4
3-(triisopropylsilyl)propiolic acid

: 1294437-54-9
N-(2-(4-bromo-1H-indol-3-yl)ethyl)-N-(4-methoxybenzyl)-3-(triisopropylsilyl)propiolamide

Guidance literature:: With dmap; dicyclohexyl-carbodiimide; In dichloromethane; at 25 ℃;
DOI:10.1002/ejoc.201001669

Reference yield:

: 2-(4-bromo-1H-indol-3-yl)-N-(4-methoxybenzylidene)ethanamine

: 1294437-54-9
N-(2-(4-bromo-1H-indol-3-yl)ethyl)-N-(4-methoxybenzyl)-3-(triisopropylsilyl)propiolamide

Guidance literature:: Multi-step reaction with 2 steps

1: sodium tetrahydroborate / ethanol / 25 °C

2: dmap; dicyclohexyl-carbodiimide / dichloromethane / 25 °C

With dmap; sodium tetrahydroborate; dicyclohexyl-carbodiimide; In ethanol; dichloromethane;
DOI:10.1002/ejoc.201001669

Reference yield:

: 123-11-5
4-methoxy-benzaldehyde

: 1294437-54-9
N-(2-(4-bromo-1H-indol-3-yl)ethyl)-N-(4-methoxybenzyl)-3-(triisopropylsilyl)propiolamide

Guidance literature:: Multi-step reaction with 3 steps

1: toluene / 3 h / Reflux

2: sodium tetrahydroborate / ethanol / 25 °C

3: dmap; dicyclohexyl-carbodiimide / dichloromethane / 25 °C

With dmap; sodium tetrahydroborate; dicyclohexyl-carbodiimide; In ethanol; dichloromethane; toluene;
DOI:10.1002/ejoc.201001669