(R)-ethyl 7-(7-methoxy-4-(1-(4-methoxyphenyl)ethylamino)quinazolin-6-yloxy)heptanoate

Base Information

Chemical Name:(R)-ethyl 7-(7-methoxy-4-(1-(4-methoxyphenyl)ethylamino)quinazolin-6-yloxy)heptanoate
CAS No.:1012057-79-2
Molecular Formula:C₂₇H₃₅N₃O₅
Molecular Weight:481.592
Hs Code.:

Synonyms:(R)-ethyl 7-(7-methoxy-4-(1-(4-methoxyphenyl)ethylamino)quinazolin-6-yloxy)heptanoate

Suppliers and Price of (R)-ethyl 7-(7-methoxy-4-(1-(4-methoxyphenyl)ethylamino)quinazolin-6-yloxy)heptanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (R)-ethyl 7-(7-methoxy-4-(1-(4-methoxyphenyl)ethylamino)quinazolin-6-yloxy)heptanoate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (R)-ethyl 7-(7-methoxy-4-(1-(4-methoxyphenyl)ethylamino)quinazolin-6-yloxy)heptanoate

There total 6 articles about (R)-ethyl 7-(7-methoxy-4-(1-(4-methoxyphenyl)ethylamino)quinazolin-6-yloxy)heptanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

: 1012057-78-1
(R)-7-methoxy-4-(1-(4-methoxyphenyl)ethylamino)quinazolin-6-ol

: 29823-18-5
ethyl 7-bromoheptanoate

: 1012057-79-2
(R)-ethyl 7-(7-methoxy-4-(1-(4-methoxyphenyl)ethylamino)quinazolin-6-yloxy)heptanoate

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 60 ℃; for 3h;

Reference yield:

: 230955-75-6
6-acetoxy-4-chloro-7-methoxyquinazoline

: 1012057-79-2
(R)-ethyl 7-(7-methoxy-4-(1-(4-methoxyphenyl)ethylamino)quinazolin-6-yloxy)heptanoate

Guidance literature:: Multi-step reaction with 2 steps

1: isopropyl alcohol / 60 °C

2: potassium carbonate / N,N-dimethyl-formamide / 3 h / 60 °C

With potassium carbonate; In N,N-dimethyl-formamide; isopropyl alcohol;

Reference yield:

: 179688-52-9
6-hydroxy-7-methoxyquinazolin-4(3H)-one

: 1012057-79-2
(R)-ethyl 7-(7-methoxy-4-(1-(4-methoxyphenyl)ethylamino)quinazolin-6-yloxy)heptanoate

Guidance literature:: Multi-step reaction with 4 steps

1: pyridine / 3 h / Heating / reflux

2: trichlorophosphate / 3 h / Heating / reflux

3: isopropyl alcohol / 60 °C

4: potassium carbonate / N,N-dimethyl-formamide / 3 h / 60 °C

With pyridine; potassium carbonate; trichlorophosphate; In N,N-dimethyl-formamide; isopropyl alcohol;