Technology Process of (+)-(4S,5S,RS)-t-butyl 4-benzyloxy-5-(4-methylphenyl)sulphinyl decanoate
There total 6 articles about (+)-(4S,5S,RS)-t-butyl 4-benzyloxy-5-(4-methylphenyl)sulphinyl decanoate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 1.) LDA / 1.) THF, -78 deg C 2.) THF, -78 deg C, 10 min.
2: 25 percent / NaBH4, aq. NH3 / methanol / 0.17 h / Ambient temperature; further reag.: DIBAH, DIBAH with ZnCl2 or CdCl2 in THF, hexane at -78 deg C
3: 85 percent / sodium hydride / dimethylformamide / 0.17 h / Ambient temperature
With
ammonium hydroxide; sodium tetrahydroborate; sodium hydride; lithium diisopropyl amide;
In
methanol; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)86906-4
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 1.) Mg, iodine / 1.) ether, 2 h 2.) benzene, RT, 30 min.
2: 1.) LDA / 1.) THF, -78 deg C 2.) THF, -78 deg C, 10 min.
3: 25 percent / NaBH4, aq. NH3 / methanol / 0.17 h / Ambient temperature; further reag.: DIBAH, DIBAH with ZnCl2 or CdCl2 in THF, hexane at -78 deg C
4: 85 percent / sodium hydride / dimethylformamide / 0.17 h / Ambient temperature
With
ammonium hydroxide; sodium tetrahydroborate; iodine; sodium hydride; magnesium; lithium diisopropyl amide;
In
methanol; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(01)86906-4
