14734-25-9

Basic information

• Product Name: TERT-BUTYL METHYL SUCCINATE 97
• Synonyms: TERT-BUTYL METHYL SUCCINATE 97;tert-Butyl methyl succinate 97%
• CAS NO: 14734-25-9
• Molecular Formula: C₉H₁₆O₄
• Molecular Weight: 188.221
• Product Categories: C8 to C9;Carbonyl Compounds;Esters;Building Blocks;C8 to C9;Carbonyl Compounds;Chemical Synthesis;Organic Building Blocks
• Mol File: 14734-25-9.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 85-95 °C20 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: /
• Density: 1.022 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.301mmHg at 25°C
• Refractive Index: n20/D 1.421(lit.)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: TERT-BUTYL METHYL SUCCINATE 97(CAS DataBase Reference)
• NIST Chemistry Reference: TERT-BUTYL METHYL SUCCINATE 97(14734-25-9)
• EPA Substance Registry System: TERT-BUTYL METHYL SUCCINATE 97(14734-25-9)

Safety Data

• Safety Statements: 23-24/25
• WGK Germany: 3
• RTECS: MO1360000
• Hazardous Substances Data: 14734-25-9(Hazardous Substances Data)

Usage

General Description

tert-Butyl methyl succinate is an ester. Mixture of its threo- and erythro- isomeric forms were obtained by the addition reaction between tert-butyl alcohol and 4-oxo-but-3-enoate in the presence of lithium tert-butoxide (catalyst).

InChI:InChI=1/C9H16O4/c1-9(2,3)13-8(11)6-5-7(10)12-4/h5-6H2,1-4H3

Upstream product

• 1663-39-4 tert-Butyl acrylate 
• 3878-55-5 methyl hydrogen succinate 
• 115-11-7 isobutene 
• 96-32-2 bromoacetic acid methyl ester 
• 51656-70-3 (2-tert-butoxy-2-oxoethyl)zinc(II) bromide 
• 67-56-1 methanol 
• 119060-47-8 tert-Butyl 2,2-dichlorocyclopropanecarboxylate 
• 75-65-0 tert-butyl alcohol 
• 1490-25-1 succinic acid monomethylester chloride 

Downstream Products

• 59854-12-5 tert-butyl 4-hydroxybutyrate 
• 1351279-11-2 2-((2-((1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-9-(4-(tert-butoxycarbonyl)phenyl)-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11b,12,13,13a,13b-octadecahydro-1H-cyclopenta[a]chrysene-3a-carboxamido)ethyl)(methyl)amino)ethyl tert-butyl succinate 
• 14734-22-6 3-(3-Carbo-t-butoxypropionyl)-malonsaeure-diethylester 
• 115352-55-1 (+)-(4R,5S,R_S)-t-butyl 4-benzyloxy-5-(4-methylphenyl)sulphinyl decanoate 
• 115405-28-2 (+)-(4S,5S,R_S)-t-butyl 4-benzyloxy-5-(4-methylphenyl)sulphinyl decanoate 
• 115352-57-3 (-)-(4R,5S)-t-butyl 4-benzyloxy-5-(4-methylphenyl)thio decanoate 
• 115352-58-4 (-)-(4S,5S)-t-butyl 4-benzyloxy-5-(4-methylphenyl)thio decanoate 
• 115405-23-7 (4R,5R,R_S)-t-butyl-5-(4-methylphenyl)sulphinyl decanoate 
• 115405-24-8 (4R,5S,R_S)-t-butyl-5-(4-methylphenyl)sulphinyl decanoate 
• 115352-53-9 (+)-(4S,5R,R_S)-t-butyl-5-(4-methylphenyl)sulphinyl decanoate 
• 115405-25-9 (4S,5S,R_S)-t-butyl-5-(4-methylphenyl)sulphinyl decanoate 
• 115352-60-8 (-)-(4S,5S)-t-butyl 4-hydroxy-5-(4-methylphenyl)thio decanoate 
• 115352-59-5 (4R,5S)-t-butyl 4-hydroxy-5-(4-methylphenyl)thio decanoate 
• 97218-68-3 (R)-4-Hydroxy-5-((R)-toluene-4-sulfinyl)-pentanoic acid tert-butyl ester 

Relevant articles and documents

Low molecular weight peptide derivatives as inhibitors of the laminin/nidogen interaction

Low molecular weight peptide derivatives which are able to act as inhibitors of the interaction between laminin and nidogen (laminin/nidogen interaction), a process for their preparation, pharmaceutical compositions prepared therefrom and their use for preparing pharmaceuticals and for identifying inhibitors of the laminin/nidogen interaction.

Reactions of Organic Anions; CXLIX. Reactions of gem-Dichlorocyclopropanes Containing an Electron-Withdrawing Substituent with Organic Anions Generated with Phase-Transfer Catalysis

gem-Dichlorocyclopropanes 1 react with C-H, O-H and S-H acids in the presence of concentrated sodium hydroxide solution and a phase-transfer catalyst to give gem-disubstituted cyclopropanes 2 or chain products 3 in 44-95percent yield.

SYNTHESIS OF THE (4S,5R)-5-HYDROXY-DECAN-4-OLIDE (L-FACTOR) AND OF THE (R)-DECAN-4-OLIDE FROM A CHIRAL SULPHOXIDE

The condensation of optically pure (+)-R-n-hexyl 4-methylphenyl sulphoxide (9) on the succinic diester (8) produced the 4-oxo-5-sulphinyl decanoate 10 which was selectively reduced to the corresponding 4-hydroxy-5-sulphinyl decanoates 11.Starting from the