methyl (R)-2-amino-3-(3,4-dihydroxyphenyl)propanoate hydrochloride salt

Base Information

Chemical Name:methyl (R)-2-amino-3-(3,4-dihydroxyphenyl)propanoate hydrochloride salt
CAS No.:889133-43-1
Molecular Formula:C₁₀H₁₃NO₄*ClH
Molecular Weight:247.678
Hs Code.:

Synonyms:methyl (R)-2-amino-3-(3,4-dihydroxyphenyl)propanoate hydrochloride salt

Suppliers and Price of methyl (R)-2-amino-3-(3,4-dihydroxyphenyl)propanoate hydrochloride salt

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemicals and raw materials
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Total 2 raw suppliers

Chemical Property of methyl (R)-2-amino-3-(3,4-dihydroxyphenyl)propanoate hydrochloride salt

Chemical Property:

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

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Hazard Codes:

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Technology Process of methyl (R)-2-amino-3-(3,4-dihydroxyphenyl)propanoate hydrochloride salt

There total 1 articles about methyl (R)-2-amino-3-(3,4-dihydroxyphenyl)propanoate hydrochloride salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 67-56-1
methanol

: 5796-17-8,90638-38-3
D-Dopa

: 889133-43-1
methyl (R)-2-amino-3-(3,4-dihydroxyphenyl)propanoate hydrochloride salt

Guidance literature:: methanol; With thionyl chloride; at 0 ℃; for 0.5h; Inert atmosphere;

D-Dopa; at 20 ℃; Inert atmosphere;
DOI:10.1016/j.ejmech.2016.08.019

Reference yield: 62.0%

: (2E)-3-[2-(3,4-dimethoxyphenyl)-7-methoxy-1-benzofuran-4-yl]prop-2-enoic acid

: 889133-43-1
methyl (R)-2-amino-3-(3,4-dihydroxyphenyl)propanoate hydrochloride salt

: methyl (R,E)-3-(3,4-dihydroxyphenyl)-2-(3-(2-(3,4-dimethoxyphenyl)-7-methoxybenzofuran-4-yl)acrylamido)propanoate

Guidance literature:: (2E)-3-[2-(3,4-dimethoxyphenyl)-7-methoxy-1-benzofuran-4-yl]prop-2-enoic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; N,N-dimethyl-formamide; at 0 ℃; for 0.25h;

methyl (R)-2-amino-3-(3,4-dihydroxyphenyl)propanoate hydrochloride salt; With triethylamine; In dichloromethane; N,N-dimethyl-formamide; at 20 ℃; Inert atmosphere;
DOI:10.1016/j.ejmech.2016.08.019

Reference yield: 16.0%

: 331-39-5,501-16-6
caffeic acid

: 889133-43-1
methyl (R)-2-amino-3-(3,4-dihydroxyphenyl)propanoate hydrochloride salt

: 618460-38-1
D-clovamide methyl ester

Guidance literature:: caffeic acid; With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; N,N-dimethyl-formamide; for 0.25h; Inert atmosphere; Cooling with ice;

methyl (R)-2-amino-3-(3,4-dihydroxyphenyl)propanoate hydrochloride salt; With triethylamine; In dichloromethane; N,N-dimethyl-formamide; at 20 ℃; for 12h; Inert atmosphere;
DOI:10.1016/j.bmc.2018.04.044