4-[5-(3,5-dichlorophenyl)-4-methyl-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]-2-methylbenzoic acid methyl ester

Base Information

Chemical Name:4-[5-(3,5-dichlorophenyl)-4-methyl-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]-2-methylbenzoic acid methyl ester
CAS No.:1097633-38-9
Molecular Formula:C₂₀H₁₆Cl₂F₃NO₃
Molecular Weight:446.253
Hs Code.:

Synonyms:4-[5-(3,5-dichlorophenyl)-4-methyl-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]-2-methylbenzoic acid methyl ester

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Chemical Property of 4-[5-(3,5-dichlorophenyl)-4-methyl-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]-2-methylbenzoic acid methyl ester

Chemical Property:

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Technology Process of 4-[5-(3,5-dichlorophenyl)-4-methyl-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]-2-methylbenzoic acid methyl ester

There total 1 articles about 4-[5-(3,5-dichlorophenyl)-4-methyl-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]-2-methylbenzoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 864736-32-3
4-[5-(3,5-dichloro-phenyl)-5-trifluoromethyl-4,5-dihydro-isoxazol-3-yl]-2-methyl-benzoic acid methyl ester

: 74-88-4
methyl iodide

: 1097633-38-9
4-[5-(3,5-dichlorophenyl)-4-methyl-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]-2-methylbenzoic acid methyl ester

Guidance literature:: 4-[5-(3,5-dichloro-phenyl)-5-trifluoromethyl-4,5-dihydro-isoxazol-3-yl]-2-methyl-benzoic acid methyl ester; With n-butyllithium; diisopropylamine; In tetrahydrofuran; hexane; at -85 - 0 ℃; Inert atmosphere;

methyl iodide; at -85 ℃; for 1.5h;

Reference yield:

: 1097633-38-9
4-[5-(3,5-dichlorophenyl)-4-methyl-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]-2-methylbenzoic acid methyl ester

: 1097633-39-0
4-(5-(3,5-dichlorophenyl)-4-methyl-5-trifluoromethyl-4,5-dihydroisoxazole-3-yl)-2-methyl benzoic acid

Guidance literature:: 4-[5-(3,5-dichlorophenyl)-4-methyl-5-trifluoromethyl-4,5-dihydroisoxazol-3-yl]-2-methylbenzoic acid methyl ester; With water; potassium hydroxide; In ethanol; for 6h; Reflux;

With hydrogenchloride; In water;