(S)-N-(2-mercaptoethyl)-6-(3-(2-(methylamino)propyl)phenoxy)hexanamide tartrate

Base Information

Chemical Name:(S)-N-(2-mercaptoethyl)-6-(3-(2-(methylamino)propyl)phenoxy)hexanamide tartrate
CAS No.:1313762-78-5
Molecular Formula:C₄H₆O₆*C₁₈H₃₀N₂O₂S
Molecular Weight:488.602
Hs Code.:

Synonyms:(S)-N-(2-mercaptoethyl)-6-(3-(2-(methylamino)propyl)phenoxy)hexanamide tartrate

Suppliers and Price of (S)-N-(2-mercaptoethyl)-6-(3-(2-(methylamino)propyl)phenoxy)hexanamide tartrate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-N-(2-mercaptoethyl)-6-(3-(2-(methylamino)propyl)phenoxy)hexanamide tartrate

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-N-(2-mercaptoethyl)-6-(3-(2-(methylamino)propyl)phenoxy)hexanamide tartrate

There total 9 articles about (S)-N-(2-mercaptoethyl)-6-(3-(2-(methylamino)propyl)phenoxy)hexanamide tartrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 87-69-4,138508-61-9
L-Tartaric acid

: 1313762-89-8
(S)-6-((3-(2-methylamino)propyl)phenoxy)-N-(2-(tritylthio)ethyl)hexanamide

: 1313762-78-5
(S)-N-(2-mercaptoethyl)-6-(3-(2-(methylamino)propyl)phenoxy)hexanamide tartrate

Guidance literature:: (S)-6-((3-(2-methylamino)propyl)phenoxy)-N-(2-(tritylthio)ethyl)hexanamide; With mercury(II) diacetate; In ethanol; at 20 ℃; Cooling with ice;

With hydrogen sulfide; In ethanol; for 2h;

L-Tartaric acid; In ethanol; Inert atmosphere;
DOI:10.1021/jm2004943

Reference yield:

: 1338381-55-7
C₄₂H₅₂N₂O₄S

: 1313762-78-5
(S)-N-(2-mercaptoethyl)-6-(3-(2-(methylamino)propyl)phenoxy)hexanamide tartrate

Guidance literature:: Multi-step reaction with 2 steps

1.1: trifluoroacetic acid / dichloromethane / 0.25 h / 20 °C

2.1: mercury(II) diacetate / ethanol / 20 °C / Cooling with ice

2.2: 2 h

2.3: Inert atmosphere

With mercury(II) diacetate; trifluoroacetic acid; In ethanol; dichloromethane;
DOI:10.1021/jm2004943

Reference yield:

: 1313762-85-4
(S)-3-(2-(methylamino)propyl)phenol hydrobromide

: 1313762-78-5
(S)-N-(2-mercaptoethyl)-6-(3-(2-(methylamino)propyl)phenoxy)hexanamide tartrate

Guidance literature:: Multi-step reaction with 5 steps

1.1: triethylamine / methanol / 0.5 h / Reflux

2.1: sodium hydride / hexanes; N,N-dimethyl-formamide / 16 h

3.1: lithium hydroxide monohydrate; water / tetrahydrofuran; methanol / 8 h / Reflux

4.1: 1-hydroxy-7-aza-benzotriazole; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 0 - 20 °C / Inert atmosphere

5.1: mercury(II) diacetate / ethanol / 20 °C / Cooling with ice

5.2: 2 h

5.3: Inert atmosphere

With 1-hydroxy-7-aza-benzotriazole; lithium hydroxide monohydrate; mercury(II) diacetate; water; sodium hydride; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; In tetrahydrofuran; methanol; hexanes; ethanol; N,N-dimethyl-formamide;
DOI:10.1021/jm2004943