Acetic acid (E)-(4R,5R)-7-(tert-butyl-dimethyl-silanyloxy)-4,5-bis-(4-methoxy-benzyloxy)-2-methyl-hept-2-enyl ester

Base Information

Chemical Name:Acetic acid (E)-(4R,5R)-7-(tert-butyl-dimethyl-silanyloxy)-4,5-bis-(4-methoxy-benzyloxy)-2-methyl-hept-2-enyl ester
CAS No.:641613-72-1
Molecular Formula:C₃₂H₄₈O₇Si
Molecular Weight:572.814
Hs Code.:

Synonyms:Acetic acid (E)-(4R,5R)-7-(tert-butyl-dimethyl-silanyloxy)-4,5-bis-(4-methoxy-benzyloxy)-2-methyl-hept-2-enyl ester

Suppliers and Price of Acetic acid (E)-(4R,5R)-7-(tert-butyl-dimethyl-silanyloxy)-4,5-bis-(4-methoxy-benzyloxy)-2-methyl-hept-2-enyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Acetic acid (E)-(4R,5R)-7-(tert-butyl-dimethyl-silanyloxy)-4,5-bis-(4-methoxy-benzyloxy)-2-methyl-hept-2-enyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Acetic acid (E)-(4R,5R)-7-(tert-butyl-dimethyl-silanyloxy)-4,5-bis-(4-methoxy-benzyloxy)-2-methyl-hept-2-enyl ester

There total 12 articles about Acetic acid (E)-(4R,5R)-7-(tert-butyl-dimethyl-silanyloxy)-4,5-bis-(4-methoxy-benzyloxy)-2-methyl-hept-2-enyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 108-24-7
acetic anhydride

: (E)-(4R,5R)-7-(tert-Butyl-dimethyl-silanyloxy)-4,5-bis-(4-methoxy-benzyloxy)-2-methyl-hept-2-en-1-ol

: 641613-72-1
Acetic acid (E)-(4R,5R)-7-(tert-butyl-dimethyl-silanyloxy)-4,5-bis-(4-methoxy-benzyloxy)-2-methyl-hept-2-enyl ester

Guidance literature:: With triethylamine; In dichloromethane; at 20 ℃;
DOI:10.1016/j.tetlet.2003.09.141

Reference yield:

: 73842-99-6
3-tert-butyldimethylsilyloxy-1-propanol

: 641613-72-1
Acetic acid (E)-(4R,5R)-7-(tert-butyl-dimethyl-silanyloxy)-4,5-bis-(4-methoxy-benzyloxy)-2-methyl-hept-2-enyl ester

Guidance literature:: Multi-step reaction with 9 steps

1: PCC / CH₂Cl₂ / 20 °C

2: 13.2 g / benzene / 24 h / Heating

3: (dihydroquinidine)2-phthalazine; potassium osmate; aq. potassium ferricyanide / K₂CO₃ / 2-methyl-propan-2-ol / 12 h / 20 °C

4: BF₃*Et₂O / CH₂Cl₂ / 0.5 h / 0 °C

5: 1.33 g / LiAlH₄ / diethyl ether / 1 h / 20 °C

6: DMSO; oxalyl chloride; Et₃N / CH₂Cl₂ / -78 - 20 °C

7: 546 mg / CH₂Cl₂ / 4 h / Heating

8: DIBAL / diethyl ether / 12 h / -78 - 20 °C

9: 1.18 g / Et₃N; DMAP / CH₂Cl₂ / 3 h / 20 °C

With dmap; potassium osmate(VI); lithium aluminium tetrahydride; oxalyl dichloride; boron trifluoride diethyl etherate; diisobutylaluminium hydride; dimethyl sulfoxide; 1,4-bis(9-O-dihydroquinidine)phthalazine; triethylamine; pyridinium chlorochromate; potassium hexacyanoferrate(III); potassium carbonate; In diethyl ether; dichloromethane; tert-butyl alcohol; benzene; 3: Sharpless asymmetric dihydroxylation / 6: Swern oxidation / 7: Wittig olefination;
DOI:10.1002/chem.200500892

Reference yield:

: 89922-82-7
3-(tert-butyldimethylsilanyloxy)propionaldehyde

: 641613-72-1
Acetic acid (E)-(4R,5R)-7-(tert-butyl-dimethyl-silanyloxy)-4,5-bis-(4-methoxy-benzyloxy)-2-methyl-hept-2-enyl ester

Guidance literature:: Multi-step reaction with 8 steps

1: 13.2 g / benzene / 24 h / Heating

2: (dihydroquinidine)2-phthalazine; potassium osmate; aq. potassium ferricyanide / K₂CO₃ / 2-methyl-propan-2-ol / 12 h / 20 °C

3: BF₃*Et₂O / CH₂Cl₂ / 0.5 h / 0 °C

4: 1.33 g / LiAlH₄ / diethyl ether / 1 h / 20 °C

5: DMSO; oxalyl chloride; Et₃N / CH₂Cl₂ / -78 - 20 °C

6: 546 mg / CH₂Cl₂ / 4 h / Heating

7: DIBAL / diethyl ether / 12 h / -78 - 20 °C

8: 1.18 g / Et₃N; DMAP / CH₂Cl₂ / 3 h / 20 °C

With dmap; potassium osmate(VI); lithium aluminium tetrahydride; oxalyl dichloride; boron trifluoride diethyl etherate; diisobutylaluminium hydride; dimethyl sulfoxide; 1,4-bis(9-O-dihydroquinidine)phthalazine; triethylamine; potassium hexacyanoferrate(III); potassium carbonate; In diethyl ether; dichloromethane; tert-butyl alcohol; benzene; 2: Sharpless asymmetric dihydroxylation / 5: Swern oxidation / 6: Wittig olefination;
DOI:10.1002/chem.200500892