1(4H)-Pyridinecarboxylic acid, 4-(2-propenyl)-, methyl ester (9CI)

Base Information

• Chemical Name: 1(4H)-Pyridinecarboxylic acid, 4-(2-propenyl)-, methyl ester (9CI)
• CAS No.: 95382-26-6
• Molecular Formula: C₁₀H₁₃NO₂
• Molecular Weight: 179.219
• Hs Code.: 2933399090
• Mol file: 95382-26-6.mol

Synonyms:1(4H)-Pyridinecarboxylicacid, 4-(2-propenyl)-, methyl ester (9CI)

Chemical Property of 1(4H)-Pyridinecarboxylic acid, 4-(2-propenyl)-, methyl ester (9CI)

Chemical Property:

• PSA: 29.54000
• LogP: 2.22600

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1(4H)-Pyridinecarboxylic acid, 4-(2-propenyl)-, methyl ester (9CI)

There total 3 articles about 1(4H)-Pyridinecarboxylic acid, 4-(2-propenyl)-, methyl ester (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

pyridine (110-86-1) + allyltributylstanane (24850-33-7) + methyl chloroformate (79-22-1) → 2-allyl-1-(methoxycarbonyl)-1,2-dihydropyridine (94161-80-5) + 4-allyl-1-methylcarboxylate-1,4-dihydropyridine (95382-26-6)

Guidance literature:

In dichloromethane; at 0 ℃; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1021/jo00250a018

Reference yield:

1-(methoxycarbonyl)pyridine-1-ium chloride (86950-96-1) + allylmagnesium bromide (1730-25-2) → 2-allyl-1-(methoxycarbonyl)-1,2-dihydropyridine (94161-80-5) + 4-allyl-1-methylcarboxylate-1,4-dihydropyridine (95382-26-6)

Guidance literature:

at -78 ℃; Yield given. Yields of byproduct given. Title compound not separated from byproducts;

DOI:10.1021/jo00250a018

Reference yield:

4C5H5N*2C8H10N(1-)*Ca(2+) + methyl chloroformate (79-22-1) → 4-allyl-1-methylcarboxylate-1,4-dihydropyridine (95382-26-6)

Guidance literature:

Inert atmosphere;

DOI:10.1002/anie.201003704

upstream raw materials:

pyridine

allyltributylstanane

methyl chloroformate

1-(methoxycarbonyl)pyridine-1-ium chloride