2-Bromo-6-methylpyrazino[2,3-b]pyrazine

Base Information

• Chemical Name: 2-Bromo-6-methylpyrazino[2,3-b]pyrazine
• CAS No.: 91225-51-3
• Molecular Formula: C7H5 Br N4
• Molecular Weight: 225.047
• Hs Code.: 2933990090
• Mol file: 91225-51-3.mol

Synonyms:2-broMo-6-Methyl-[1,4]diazino[2,3-b]pyrazine

Chemical Property of 2-Bromo-6-methylpyrazino[2,3-b]pyrazine

Chemical Property:

• PSA: 51.56000
• LogP: 1.49070
• Storage Temp.: 2-8°C

Purity/Quality:

98%min ^*data from raw suppliers

2-Bromo-6-methylpyrazino[2,3-b]pyrazine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-Bromo-6-methylpyrazino[2,3-b]pyrazine

There total 1 articles about 2-Bromo-6-methylpyrazino[2,3-b]pyrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-bromopyrazine-2,3-diamine (89123-58-0) + 2-oxopropanal (78-98-8) → 2-bromo-6-methylpyrazino<2,3-b>pyrazine (91225-51-3)

Guidance literature:

In ethanol; at 20 ℃; for 16h;

DOI:10.1071/CH9841057

Reference yield: 84.0%

2-bromo-6-methylpyrazino<2,3-b>pyrazine (91225-51-3) + 4-(diphenylamino)phenyl boronic acid (201802-67-7) → C25H19N5

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In ethanol; water; toluene; Inert atmosphere; Reflux;

Reference yield: 84.0%

N-[1,1-biphenyl]-4-yl-N-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]-[1,1-biphenyl]-4-amine (952431-30-0) + 2-bromo-6-methylpyrazino<2,3-b>pyrazine (91225-51-3) → C37H27N5

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium carbonate; In ethanol; water; toluene; Inert atmosphere; Reflux;

upstream raw materials:

5-bromopyrazine-2,3-diamine

2-oxopropanal

Refernces