C₄₈H₅₀N₂O₁₁

Base Information

• Chemical Name: C₄₈H₅₀N₂O₁₁
• CAS No.: 1446748-43-1
• Molecular Formula: C₄₈H₅₀N₂O₁₁
• Molecular Weight: 830.932
• Mol file: 1446748-43-1.mol

Synonyms:C₄₈H₅₀N₂O₁₁

Chemical Property of C₄₈H₅₀N₂O₁₁

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₈H₅₀N₂O₁₁

There total 6 articles about C₄₈H₅₀N₂O₁₁ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

C54H64N2O11Si (1446748-42-0) → C48H50N2O11 (1446748-43-1)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; at 20 ℃; for 0.5h; Inert atmosphere;

DOI:10.1021/ol401566r

Reference yield:

5-Methyluridine (1463-10-1,642082-80-2) → C48H50N2O11 (1446748-43-1)

Guidance literature:

Multi-step reaction with 6 steps

1.1: triphenylphosphine; iodine; 1H-imidazole / tetrahydrofuran / 0 - 20 °C / Inert atmosphere

1.2: 0 - 20 °C / Inert atmosphere

2.1: 1,8-diazabicyclo[5.4.0]undec-7-ene / N,N-dimethyl-formamide / 0.5 h / 0 °C / Inert atmosphere

3.1: silver(l) oxide / dichloromethane / 0 - 20 °C / Inert atmosphere

4.1: 3-chloro-benzenecarboperoxoic acid / 2 h / 0 °C / Inert atmosphere

5.1: 2,6-dimethylpyridine / dichloromethane / 1 h / 0 °C / Inert atmosphere

6.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.5 h / 20 °C / Inert atmosphere

With 1H-imidazole; 2,6-dimethylpyridine; tetrabutyl ammonium fluoride; iodine; 1,8-diazabicyclo[5.4.0]undec-7-ene; 3-chloro-benzenecarboperoxoic acid; triphenylphosphine; silver(l) oxide; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/ol401566r

Reference yield:

C33H46N2O9Si (1446748-41-9) → C48H50N2O11 (1446748-43-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 2,6-dimethylpyridine / dichloromethane / 1 h / 0 °C / Inert atmosphere

2: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.5 h / 20 °C / Inert atmosphere

With 2,6-dimethylpyridine; tetrabutyl ammonium fluoride; In tetrahydrofuran; dichloromethane;

DOI:10.1021/ol401566r

upstream raw materials:

C₃₃H₄₆N₂O₉Si

C₅₄H₆₄N₂O₁₁Si

5-Methyluridine

C₁₈H₂₀N₂O₆

Downstream raw materials:

C₄₈H₄₈N₂O₁₀

C₃₃H₃₄N₂O₉

C₄₂H₅₁N₄O₁₀P

C₅₅H₅₆N₂O₁₃S