trans-4-tert-butylcyclohexyl 3-pyridinesulfonate

Base Information

• Chemical Name: trans-4-tert-butylcyclohexyl 3-pyridinesulfonate
• CAS No.: 117800-89-2
• Molecular Formula: C₁₅H₂₃NO₃S
• Molecular Weight: 297.419
• Mol file: 117800-89-2.mol

Synonyms:trans-4-tert-butylcyclohexyl 3-pyridinesulfonate

Chemical Property of trans-4-tert-butylcyclohexyl 3-pyridinesulfonate

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of trans-4-tert-butylcyclohexyl 3-pyridinesulfonate

There total 2 articles about trans-4-tert-butylcyclohexyl 3-pyridinesulfonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

Pyridine-3-sulfonyl chloride (16133-25-8) + trans-4-tert-butylcyclohexanol (21862-63-5) → trans-4-tert-butylcyclohexyl 3-pyridinesulfonate (117800-89-2)

Guidance literature:

In pyridine; at -10 ℃; for 1.75h;

DOI:10.1021/jo00263a024

Reference yield:

3-pyridinesulfonic acid (636-73-7) → trans-4-tert-butylcyclohexyl 3-pyridinesulfonate (117800-89-2)

Guidance literature:

Multi-step reaction with 2 steps

1: 72 percent / PCl₅, POCl₃ / 3 h / Heating

2: 77 percent / pyridine / 1.75 h / -10 °C

With phosphorus pentachloride; trichlorophosphate; In pyridine;

DOI:10.1021/jo00263a024

upstream raw materials:

Pyridine-3-sulfonyl chloride

trans-4-tert-butylcyclohexanol

3-pyridinesulfonic acid

Refernces