Technology Process of 1-(α-ferrocenylethyl)-1,2,4-triazole
There total 2 articles about 1-(α-ferrocenylethyl)-1,2,4-triazole which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
HCl; NH3;
In
ethanol; water;
byproducts: C7H6N2; dissolving of (C5H5)Fe(C5H4CH(CH3)C7H5N2) in ethanol on heating, addn. of soln. of 1,2,4-triazole in H2O and concd. HCl; reflux for 2.5 h, cooling, neutralizing with aq. ammonia; extn. with dimethyl ether; sepn. of org. layer, TLC chromy. using hexaneand then methanol as eluents;
DOI:10.1023/A:1021360704054
- Guidance literature:
-
With
HCl; NH3;
In
ethanol; water;
byproducts: C7H6N2; dissolving of (C5H5)Fe(C5H4CH(CH3)C7H5N2) in ethanol on heating, addn. of soln. of 1,2,4-triazole in H2O and concd. HCl; reflux for 2.5 h, cooling, neutralizing with aq. ammonia; extn. with dimethyl ether; sepn. of org layer, TLC chromy. using hexane,benzene and then methanol as eluents;
DOI:10.1023/A:1021360704054
- Guidance literature:
-
With
HCl; NH3;
In
methanol; water;
dissoving of (C5H5)Fe(C5H4CH(CH3)C2H2N3) in methanol on heating; addn. of soln. of indazole in H2O and concd. HCl; reflux for 2.5 h, cooling, neutralizing with aq. ammonia; extn. with dimethyl ether, sepn. of org. layer; monitoring by mass-spectroscopy and comparative chromy. on Silufol plate;
DOI:10.1023/A:1021360704054
