(2S)-2-{1-[(1S)-1-carboxy-2-(5-phenyl-oxazol-2-yl)-ethylcarbamoyl]-cyclopentylmethyl}-4-methoxy-butyric acid

Base Information

Chemical Name:(2S)-2-{1-[(1S)-1-carboxy-2-(5-phenyl-oxazol-2-yl)-ethylcarbamoyl]-cyclopentylmethyl}-4-methoxy-butyric acid
CAS No.:719307-81-0
Molecular Formula:C₂₄H₃₀N₂O₇
Molecular Weight:458.511
Hs Code.:

Synonyms:(2S)-2-{1-[(1S)-1-carboxy-2-(5-phenyl-oxazol-2-yl)-ethylcarbamoyl]-cyclopentylmethyl}-4-methoxy-butyric acid

Suppliers and Price of (2S)-2-{1-[(1S)-1-carboxy-2-(5-phenyl-oxazol-2-yl)-ethylcarbamoyl]-cyclopentylmethyl}-4-methoxy-butyric acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S)-2-{1-[(1S)-1-carboxy-2-(5-phenyl-oxazol-2-yl)-ethylcarbamoyl]-cyclopentylmethyl}-4-methoxy-butyric acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S)-2-{1-[(1S)-1-carboxy-2-(5-phenyl-oxazol-2-yl)-ethylcarbamoyl]-cyclopentylmethyl}-4-methoxy-butyric acid

There total 5 articles about (2S)-2-{1-[(1S)-1-carboxy-2-(5-phenyl-oxazol-2-yl)-ethylcarbamoyl]-cyclopentylmethyl}-4-methoxy-butyric acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₃₁H₄₄N₂O₇

: 719307-81-0
(2S)-2-{1-[(1S)-1-carboxy-2-(5-phenyl-oxazol-2-yl)-ethylcarbamoyl]-cyclopentylmethyl}-4-methoxy-butyric acid

Guidance literature:: C₃₁H₄₄N₂O₇; With sodium hydroxide; In methanol; at 20 ℃; for 18h;

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 18h;

Reference yield:

: 719308-09-5
(2S)-2-benzyloxycarbonylamino-3-(5-phenyl-oxazol-2-yl)-propionic acid ethyl ester

: 719307-81-0
(2S)-2-{1-[(1S)-1-carboxy-2-(5-phenyl-oxazol-2-yl)-ethylcarbamoyl]-cyclopentylmethyl}-4-methoxy-butyric acid

Guidance literature:: Multi-step reaction with 4 steps

1: hydrogen bromide; acetic acid

2: 4-methyl-morpholine; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide / dichloromethane

3: trifluoroacetic acid / dichloromethane

4: water; sodium hydroxide / 1,4-dioxane

With 4-methyl-morpholine; water; hydrogen bromide; benzotriazol-1-ol; acetic acid; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; trifluoroacetic acid; sodium hydroxide; In 1,4-dioxane; dichloromethane;
DOI:10.1016/j.bmcl.2011.03.109

Reference yield:

: 755753-54-9
(2S)-2-amino-3-(5-phenyl-oxazol-2-yl)-propionic acid ethyl ester

: 719307-81-0
(2S)-2-{1-[(1S)-1-carboxy-2-(5-phenyl-oxazol-2-yl)-ethylcarbamoyl]-cyclopentylmethyl}-4-methoxy-butyric acid

Guidance literature:: Multi-step reaction with 3 steps

1: 4-methyl-morpholine; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide / dichloromethane

2: trifluoroacetic acid / dichloromethane

3: water; sodium hydroxide / 1,4-dioxane

With 4-methyl-morpholine; water; benzotriazol-1-ol; N-(3-dimethylaminopropyl)-N-ethylcarbodiimide; trifluoroacetic acid; sodium hydroxide; In 1,4-dioxane; dichloromethane;
DOI:10.1016/j.bmcl.2011.03.109