methyl 7α,12α-diacetoxy-3α-cholan-24-oate

Base Information

• Chemical Name: methyl 7α,12α-diacetoxy-3α-cholan-24-oate
• CAS No.: 125626-98-4
• Molecular Formula: C₃₈H₅₂F₃NO₇
• Molecular Weight: 691.829
• Mol file: 125626-98-4.mol

Synonyms:methyl 7α,12α-diacetoxy-3α-cholan-24-oate

Chemical Property of methyl 7α,12α-diacetoxy-3α-cholan-24-oate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 7α,12α-diacetoxy-3α-cholan-24-oate

There total 5 articles about methyl 7α,12α-diacetoxy-3α-cholan-24-oate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl cholate (1448-36-8) → methyl 7α,12α-diacetoxy-3α-cholan-24-oate (125626-98-4)

Guidance literature:

Multi-step reaction with 4 steps

1: pyridine, dimethylaminopyridine (DMAP)

2: AcCl / methanol

3: pyridinium chlorochromate

With pyridine; dmap; acetyl chloride; pyridinium chlorochromate; In methanol;

DOI:10.1039/c39890001050

Reference yield:

methyl 3,7,12-triacetoxycholan-24-oate (6818-44-6) → methyl 7α,12α-diacetoxy-3α-cholan-24-oate (125626-98-4)

Guidance literature:

Multi-step reaction with 3 steps

1: AcCl / methanol

2: pyridinium chlorochromate

With acetyl chloride; pyridinium chlorochromate; In methanol;

DOI:10.1039/c39890001050

Reference yield:

methyl 7,12-diacetoxycholate (69889-89-0) → methyl 7α,12α-diacetoxy-3α-cholan-24-oate (125626-98-4)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridinium chlorochromate

With pyridinium chlorochromate;

DOI:10.1039/c39890001050

upstream raw materials:

methyl 3-keto-7,12-diacetylcholate

trifluoroacetic acid

cholic acid

methyl 7,12-diacetoxycholate

Downstream raw materials:

3α-(p-aminomethyl)phenyl-7α,12α-diacetoxycholan-24-oic acid

methyl 3α-(p-aminomethyl)phenyl-7α,12α-diacetoxycholan-24-oate

pentafluorophenyl 7α,12α-diacetoxy-3α-(p-tert-butoxycarbonylaminomethylphenyl)cholan-24-oate

7α,12α-diacetoxy-3α-(p-tert-butoxycarbonylaminomethylphenyl)cholan-24-oic acid