4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoro-undecanoic acid (4-methanesulfinyl-phenyl)-methyl-amide

Base Information

• Chemical Name: 4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoro-undecanoic acid (4-methanesulfinyl-phenyl)-methyl-amide
• CAS No.: 724733-03-3
• Molecular Formula: C₁₉H₁₄F₁₇NO₂S
• Molecular Weight: 643.365
• Mol file: 724733-03-3.mol

Synonyms:4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoro-undecanoic acid (4-methanesulfinyl-phenyl)-methyl-amide

Chemical Property of 4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoro-undecanoic acid (4-methanesulfinyl-phenyl)-methyl-amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoro-undecanoic acid (4-methanesulfinyl-phenyl)-methyl-amide

There total 1 articles about 4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoro-undecanoic acid (4-methanesulfinyl-phenyl)-methyl-amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoro-undecanoic acid methyl-(4-methylsulfanyl-phenyl)-amide (724733-01-1) → 4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoro-undecanoic acid (4-methanesulfinyl-phenyl)-methyl-amide (724733-03-3)

Guidance literature:

With Selectfluor; In water; acetonitrile; at 20 ℃; for 0.333333h;

DOI:10.1016/j.tetlet.2004.04.116

Reference yield: 75.0%

4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoro-undecanoic acid (4-methanesulfinyl-phenyl)-methyl-amide (724733-03-3) → 4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoro-undecanoic acid (4-mercapto-phenyl)-methyl-amide (724733-04-4)

Guidance literature:

4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoro-undecanoic acid (4-methanesulfinyl-phenyl)-methyl-amide; With trifluoroacetic anhydride; at 40 ℃; for 0.833333h;

With sodium hydroxide; In water; at 0 ℃; for 2h; Further stages.;

DOI:10.1016/j.tetlet.2004.04.116

Reference yield:

4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoro-undecanoic acid (4-methanesulfinyl-phenyl)-methyl-amide (724733-03-3) → 4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-Heptadecafluoro-undecanoic acid methyl-[4-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-ylsulfanyl)-phenyl]-amide (724733-06-6)

Guidance literature:

Multi-step reaction with 3 steps

1.1: trifluoroacetic anhydride / 0.83 h / 40 °C

1.2: 75 percent / NaOH / H₂O / 2 h / 0 °C

2.1: 100 percent / Na₂CO₃ / H₂O; ethyl acetate / 2 h / 20 °C

3.1: 100 percent / CH₃ONa / methanol / 5 h / 20 °C

With sodium methylate; sodium carbonate; trifluoroacetic anhydride; In methanol; water; ethyl acetate;

DOI:10.1016/j.tetlet.2004.04.116

upstream raw materials:

4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoro-undecanoic acid methyl-(4-methylsulfanyl-phenyl)-amide

Downstream raw materials:

4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-heptadecafluoro-undecanoic acid (4-mercapto-phenyl)-methyl-amide

4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-Heptadecafluoro-undecanoic acid methyl-[4-((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-ylsulfanyl)-phenyl]-amide

4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-Heptadecafluoro-undecanoic acid methyl-[4-((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-ylsulfanyl)-phenyl]-amide

4,4,5,5,6,6,7,7,8,8,9,9,10,10,11,11,11-Heptadecafluoro-undecanoic acid methyl-[4-((2S,3R,4S,5R,6R)-3,4,5-tris-benzyloxy-6-benzyloxymethyl-tetrahydro-pyran-2-ylsulfanyl)-phenyl]-amide