N-(4-Methoxy-2-trimethylsilanylmethyl-phenyl)-N-methyl-benzamide

Base Information

• Chemical Name: N-(4-Methoxy-2-trimethylsilanylmethyl-phenyl)-N-methyl-benzamide
• CAS No.: 117615-97-1
• Molecular Formula: C₁₉H₂₅NO₂Si
• Molecular Weight: 327.499
• Mol file: 117615-97-1.mol

Synonyms:N-(4-Methoxy-2-trimethylsilanylmethyl-phenyl)-N-methyl-benzamide

Chemical Property of N-(4-Methoxy-2-trimethylsilanylmethyl-phenyl)-N-methyl-benzamide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N-(4-Methoxy-2-trimethylsilanylmethyl-phenyl)-N-methyl-benzamide

There total 3 articles about N-(4-Methoxy-2-trimethylsilanylmethyl-phenyl)-N-methyl-benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

para-methoxynitrobenzene (100-17-4) → N-(4-Methoxy-2-trimethylsilanylmethyl-phenyl)-N-methyl-benzamide (117615-97-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 2.) LiAlH₄ / 2.) Pd/C / 1.) THF, 0 deg C 2.) rt

2: Et₃N

3: NaH

With lithium aluminium tetrahydride; sodium hydride; triethylamine; palladium on activated charcoal;

DOI:10.1039/c39880000807

Reference yield:

2-trimethylsilylmethyl-4-anisidine (114650-47-4) → N-(4-Methoxy-2-trimethylsilanylmethyl-phenyl)-N-methyl-benzamide (117615-97-1)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₃N

2: NaH

With sodium hydride; triethylamine;

DOI:10.1039/c39880000807

Reference yield:

4-methoxy-2-trimethylsilylmethylbenzanilide (117616-04-3) + methyl iodide (74-88-4) → N-(4-Methoxy-2-trimethylsilanylmethyl-phenyl)-N-methyl-benzamide (117615-97-1)

Guidance literature:

With sodium hydride; Yield given;

DOI:10.1039/c39880000807

upstream raw materials:

4-methoxy-2-trimethylsilylmethylbenzanilide

methyl iodide

para-methoxynitrobenzene

2-trimethylsilylmethyl-4-anisidine

Downstream raw materials:

5-methoxy-1-methyl-2-phenyl-1H-indole