TYR-D-ALA-GLY-PHE-D-LEU ACETATE SALT

Base Information

Chemical Name:TYR-D-ALA-GLY-PHE-D-LEU ACETATE SALT
CAS No.:94825-57-7
Molecular Formula:C₂H₄O₂*C₂₉H₃₉N₅O₇
Molecular Weight:629.711
Hs Code.:
Mol file:94825-57-7.mol

Synonyms:[D-ALA2, D-LEU5]-ENKEPHALIN ACETATE SALT;TYR-D-ALA-GLY-PHE-D-LEU ACETATE SALT;(D-ALA2, D-LEU5)-ENKEPHALIN ACETATE;(D-alanine2,D-leucine5)enkephalin

Suppliers and Price of TYR-D-ALA-GLY-PHE-D-LEU ACETATE SALT

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Sigma-Aldrich
[D-Ala2, D-Leu5]-Enkephalin acetate salt ≥95% (HPLC)
25mg
$ 330.00

Sigma-Aldrich
[D-Ala2, D-Leu5]-Enkephalin acetate salt ≥95% (HPLC)
5mg
$ 91.50

Sigma-Aldrich
[D-Ala2, D-Leu5]-Enkephalin acetate salt ≥95% (HPLC)
1mg
$ 30.50

American Custom Chemicals Corporation
[D-ALA2,D-LEU5]-ENKEPHALIN ACETATE 95.00%
25MG
$ 881.07

American Custom Chemicals Corporation
[D-ALA2,D-LEU5]-ENKEPHALIN ACETATE 95.00%
5MG
$ 714.53

American Custom Chemicals Corporation
[D-ALA2,D-LEU5]-ENKEPHALIN ACETATE 95.00%
1MG
$ 632.81

Total 6 raw suppliers

Chemical Property of TYR-D-ALA-GLY-PHE-D-LEU ACETATE SALT

Chemical Property:

PSA：237.25000
LogP:2.58070
Storage Temp.:−20°C

Purity/Quality:

99%, ^*data from raw suppliers

[D-Ala2, D-Leu5]-Enkephalin acetate salt ≥95% (HPLC) ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses [D-Ala2, D-Leu5]-Enkephalin or DADLE has been used for use in immunocomplex kinetic assay, to determine the activation of p70s6k by DADLE in the cell clones D2 and DOE and in non-transfected parental Rat-1 fibroblasts and to assess the analgesic effect of WIN55,212-2 in mice.

Technology Process of TYR-D-ALA-GLY-PHE-D-LEU ACETATE SALT

There total 8 articles about TYR-D-ALA-GLY-PHE-D-LEU ACETATE SALT which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 29842-94-2
(S)-tert-butyl 2-((S)-2-(((benzyloxy)carbonyl)amino)-3-phenylpropanamido)-4-methylpentanoate

: 94825-57-7
(D)Ala², Leu⁵-Enk acetate

Guidance literature:: Multi-step reaction with 4 steps

1: 97 percent / H₂ / 10percent Pd/C / methanol / Ambient temperature

2: 1.) N-methylmorpholine, isobutylchloroformate / 1.) THF, -15 deg C, 2 min, 2.) THF, 0 deg C, 30 min; r.t., 3 h

3: 90percent aq. trifluoroacetic acid / 1.5 h / Ambient temperature

4: H₂ / 10percent Pd/C / Ambient temperature

With 4-methyl-morpholine; hydrogen; trifluoroacetic acid; isobutyl chloroformate; palladium on activated charcoal; In methanol;

Reference yield:

: 74085-05-5
tert-butylbenzyloxycarbonyl-(D)alanylglicinate

: 94825-57-7
(D)Ala², Leu⁵-Enk acetate

Guidance literature:: Multi-step reaction with 6 steps

1: 99 percent / H₂ / 10percent Pd/C / methanol / 4 h / Ambient temperature

2: 1.) N-methylmorpholine, isobutyl chloroformate / 1.) THF, -15 deg C, 2 min, 2.) THF, 0 deg C, 30 min; r.t., 20 h

3: 85 percent / 90percent aq. trifluoroacetic acid / 1 h / Ambient temperature

4: 1.) N-methylmorpholine, isobutylchloroformate / 1.) THF, -15 deg C, 2 min, 2.) THF, 0 deg C, 30 min; r.t., 3 h

5: 90percent aq. trifluoroacetic acid / 1.5 h / Ambient temperature

6: H₂ / 10percent Pd/C / Ambient temperature

With 4-methyl-morpholine; hydrogen; trifluoroacetic acid; isobutyl chloroformate; palladium on activated charcoal; In methanol;

Reference yield:

: 28635-78-1
L-phenylalanyl-L-leucine tert-butyl ester

: 94825-57-7
(D)Ala², Leu⁵-Enk acetate

Guidance literature:: Multi-step reaction with 3 steps

1: 1.) N-methylmorpholine, isobutylchloroformate / 1.) THF, -15 deg C, 2 min, 2.) THF, 0 deg C, 30 min; r.t., 3 h

2: 90percent aq. trifluoroacetic acid / 1.5 h / Ambient temperature

3: H₂ / 10percent Pd/C / Ambient temperature

With 4-methyl-morpholine; hydrogen; trifluoroacetic acid; isobutyl chloroformate; palladium on activated charcoal;