C₁₉H₁₁Cl₂N₅

Base Information

• Chemical Name: C₁₉H₁₁Cl₂N₅
• CAS No.: 1197849-65-2
• Molecular Formula: C₁₉H₁₁Cl₂N₅
• Molecular Weight: 380.236
• Mol file: 1197849-65-2.mol

Synonyms:C₁₉H₁₁Cl₂N₅

Chemical Property of C₁₉H₁₁Cl₂N₅

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of C₁₉H₁₁Cl₂N₅

There total 2 articles about C₁₉H₁₁Cl₂N₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4,6-dichloropyrimidine (1193-21-1) + 2-(2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)acetonitrile (17744-99-9) → C19H11Cl2N5 (1197849-65-2)

Guidance literature:

With potassium tert-butylate; In acetonitrile; at 20 ℃;

Reference yield:

3-(chloromethyl)-2-(4-chlorophenyl)imidazo[1,2-a]pyridine hydrochloride → C19H11Cl2N5 (1197849-65-2)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium iodide / tetra-n-butylammonium cyanide / acetonitrile / 20 °C

2: potassium tert-butylate / acetonitrile / 20 °C

With potassium tert-butylate; sodium iodide; tetra-n-butylammonium cyanide; In acetonitrile;

Reference yield:

C19H11Cl2N5 (1197849-65-2) → 6-((2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)pyrimidin-4-ol (1197849-66-3)

Guidance literature:

C₁₉H₁₁Cl₂N₅; With trifluoroacetic acid; In water; at 150 ℃; for 0.0833333h; Microwave irradiation;

With sodium hydrogencarbonate; In water; ethyl acetate;

upstream raw materials:

4,6-dichloropyrimidine

2-(2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)acetonitrile

Downstream raw materials:

6-((2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)pyrimidin-4-ol

2-(4-chlorophenyl)-3-((6-chloropyrimidin-4-yl)methyl)imidazo[1,2-a]pyridine

N₁-(6-((2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)methyl)pyrimidin-4-yl)-N₂,N₂-dimethylethane-1,2-diamine

Refernces