Imidazo(1,2-a)pyridine-3-acetonitrile, 2-(p-chlorophenyl)-

Base Information

Chemical Name:Imidazo(1,2-a)pyridine-3-acetonitrile, 2-(p-chlorophenyl)-
CAS No.:17744-99-9
Molecular Formula:C15H10 Cl N3
Molecular Weight:267.717
Hs Code.:2933990090
DSSTox Substance ID:DTXSID10170309
Nikkaji Number:J40.941C
Wikidata:Q83040220
Mol file:17744-99-9.mol

Synonyms:17744-99-9;Imidazo(1,2-a)pyridine-3-acetonitrile, 2-(p-chlorophenyl)-;BRN 0804388;2-[2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl]acetonitrile;2-(p-Chlorophenyl)-3-cyanomethylimidazo(1,2-a)pyridine;Imidazo(1,2-a)pyridine, 2-(p-chlorophenyl)-3-cyanomethyl;C15H10ClN3;2-(2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)acetonitrile;Imidazo[1,2-a]pyridine-3-acetonitrile, 2-(p-chlorophenyl)-;SCHEMBL1430434;DTXSID10170309;LS-80226;2-(Chlorophenyl)imidazo(1,2-a)pyridine-3-acetonile;2-(p-Chlorophenyl)imidazo[1,2-a]pyridine-3-acetonitrile;[2-(4-Chlorophenyl)imidazo[1,2-a]pyridin-3-yl]acetonitrile

Suppliers and Price of Imidazo(1,2-a)pyridine-3-acetonitrile, 2-(p-chlorophenyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Imidazo(1,2-a)pyridine-3-acetonitrile, 2-(p-chlorophenyl)-

Chemical Property:

PSA：41.09000
Density:1.27g/cm³
LogP:3.72078
XLogP3:3.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:267.0563250
Heavy Atom Count:19
Complexity:356

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=NC(=C(N2C=C1)CC#N)C3=CC=C(C=C3)Cl

Technology Process of Imidazo(1,2-a)pyridine-3-acetonitrile, 2-(p-chlorophenyl)-

There total 8 articles about Imidazo(1,2-a)pyridine-3-acetonitrile, 2-(p-chlorophenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 38922-74-6
2-(4-chlorophenyl)imidazolo[1,2-a]pyridine

: 590-17-0
cyanomethyl bromide

: 17744-99-9
2-(2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)acetonitrile

Guidance literature:: With fac-tris(2-phenylpyridinato-N,C₂')iridium(III); sodium hydrogencarbonate; In dimethyl sulfoxide; at 20 ℃; for 12h; regioselective reaction; Schlenk technique; Inert atmosphere; Irradiation;
DOI:10.1021/acs.joc.7b00750

Reference yield: 82.0%

: 773837-37-9
sodium cyanide

: 3-(chloromethyl)-2-(4-chlorophenyl)imidazo[1,2-a]pyridine hydrochloride

: 17744-99-9
2-(2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)acetonitrile

Guidance literature:: With sodium iodide; tetra-n-butylammonium cyanide; In acetonitrile; at 20 ℃;

Reference yield: 67.0%

: 38922-74-6
2-(4-chlorophenyl)imidazolo[1,2-a]pyridine

: 75-05-8,26809-02-9
acetonitrile

: 17744-99-9
2-(2-(4-chlorophenyl)imidazo[1,2-a]pyridin-3-yl)acetonitrile

Guidance literature:: With ferrocene; bis(1-methyl-1-phenylethyl)peroxide; at 20 - 100 ℃; for 20h; Inert atmosphere; Sealed tube;
DOI:10.1021/acs.orglett.7b00678