(3-methoxyphenyl)magnesium bromide

Base Information

• Chemical Name: (3-methoxyphenyl)magnesium bromide
• CAS No.: 872088-08-9
• Molecular Formula: C₉H₉IMgO₂
• Molecular Weight: 300.379
• Mol file: 872088-08-9.mol

Synonyms:(3-methoxyphenyl)magnesium bromide

Chemical Property of (3-methoxyphenyl)magnesium bromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (3-methoxyphenyl)magnesium bromide

There total 1 articles about (3-methoxyphenyl)magnesium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-iodobenzoic acid ethyl ester (51934-41-9) → (3-methoxyphenyl)magnesium bromide (872088-08-9)

Guidance literature:

With diisopropylmagnesium; In tetrahydrofuran; tert-butyl methyl ether; at -40 ℃; for 1h;

Reference yield: 87.0%

(3-methoxyphenyl)magnesium bromide (872088-08-9) + 6-Chloronicotinoyl chloride (58757-38-3)

Guidance literature:

With Bis<2-(N,N-dimethylamino)aethyl>aether; In tetrahydrofuran; cooling;

DOI:10.1021/ol052150q

Reference yield: 65.0%

(3-methoxyphenyl)magnesium bromide (872088-08-9) + benzyl 2-bromopropionate (3017-53-6) → (S)-ethyl 4-(1-(benzyloxy)-1-oxopropan-2-yl)benzoate

Guidance literature:

benzyl 2-bromopropionate; With (4S,4S')-(-)-2,2'-(1-methylethylidene)bis[4,5-dihydro-4-(phenylmethyl)oxazole]; cobalt(II) iodide; In tetrahydrofuran; diethyl ether; at 25 ℃; for 0.0833333h; Schlenk technique; Inert atmosphere;

(3-methoxyphenyl)magnesium bromide; In tetrahydrofuran; diethyl ether; at -80 ℃; for 24h; Inert atmosphere;

DOI:10.1021/ja5109084

upstream raw materials:

4-iodobenzoic acid ethyl ester

Downstream raw materials:

ethyl p-(hydroxy(phenyl)methyl)benzoate

4-(1,3,7-trimethyl-2,6-dioxo-2,3,6,7-tetrahydro-1H-purin-8-yl)-benzoic acid ethyl ester

ethyl 4′-formyl[1,1′-biphenyl]-4-carboxylate

Refernces