N-(1-(4-bromo-3-methoxyphenyl)-1H-pyrazol-3-yl)-2,2,2-trifluoro-N-methylacetamide

Base Information

Chemical Name:N-(1-(4-bromo-3-methoxyphenyl)-1H-pyrazol-3-yl)-2,2,2-trifluoro-N-methylacetamide
CAS No.:1620515-91-4
Molecular Formula:C₁₃H₁₁BrF₃N₃O₂
Molecular Weight:378.148
Hs Code.:

Synonyms:N-(1-(4-bromo-3-methoxyphenyl)-1H-pyrazol-3-yl)-2,2,2-trifluoro-N-methylacetamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-(1-(4-bromo-3-methoxyphenyl)-1H-pyrazol-3-yl)-2,2,2-trifluoro-N-methylacetamide

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Technology Process of N-(1-(4-bromo-3-methoxyphenyl)-1H-pyrazol-3-yl)-2,2,2-trifluoro-N-methylacetamide

There total 3 articles about N-(1-(4-bromo-3-methoxyphenyl)-1H-pyrazol-3-yl)-2,2,2-trifluoro-N-methylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1620515-90-3
N-(1-(4-bromo-3-methoxyphenyl)-1H-pyrazol-3-yl)-2,2,2-trifluoroacetamide

: 74-88-4
methyl iodide

: 1620515-91-4
N-(1-(4-bromo-3-methoxyphenyl)-1H-pyrazol-3-yl)-2,2,2-trifluoro-N-methylacetamide

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃;

Reference yield:

: 755027-18-0
1-bromo-4-iodo-2-methoxybenzene

: 1620515-91-4
N-(1-(4-bromo-3-methoxyphenyl)-1H-pyrazol-3-yl)-2,2,2-trifluoro-N-methylacetamide

Guidance literature:: Multi-step reaction with 3 steps

1: hydroxybenzaldoxime; copper(I) oxide; caesium carbonate / N,N-dimethyl-formamide / 95 °C / Inert atmosphere

2: pyridine / dichloromethane / 3 h / 20 °C

3: potassium carbonate / N,N-dimethyl-formamide / 20 °C

With pyridine; copper(I) oxide; potassium carbonate; caesium carbonate; hydroxybenzaldoxime; In dichloromethane; N,N-dimethyl-formamide;

Reference yield:

: 1562339-57-4
1-(4-bromo-3-methoxyphenyl)-1H-pyrazol-3-amine

: 1620515-91-4
N-(1-(4-bromo-3-methoxyphenyl)-1H-pyrazol-3-yl)-2,2,2-trifluoro-N-methylacetamide

Guidance literature:: Multi-step reaction with 2 steps

1: pyridine / dichloromethane / 3 h / 20 °C

2: potassium carbonate / N,N-dimethyl-formamide / 20 °C

With pyridine; potassium carbonate; In dichloromethane; N,N-dimethyl-formamide;