1-(2,2,2-Trifluoroacetyl)pyrrolidin-2-one

Base Information

Chemical Name:1-(2,2,2-Trifluoroacetyl)pyrrolidin-2-one
CAS No.:94363-57-2
Molecular Formula:C6H6 F3 N O2
Molecular Weight:181.114
Hs Code.:2933790090
DSSTox Substance ID:DTXSID60535328
Wikidata:Q82409596
Mol file:94363-57-2.mol

Synonyms:1-(2,2,2-trifluoroacetyl)pyrrolidin-2-one;94363-57-2;1-(TRIFLUOROACETYL)-2-PYRROLIDINONE;MFCD00462347;SCHEMBL3054980;DTXSID60535328;1-(Trifluoroacetyl)pyrrolidin-2-one;PS-18950;SY297312;1-(2,2,2-trifluoroacetyl)-pyrrolidin-2-one;F89459

Suppliers and Price of 1-(2,2,2-Trifluoroacetyl)pyrrolidin-2-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-(TRIFLUOROACETYL)-2-PYRROLIDINONE 95.00%
5MG
$ 503.23

Total 4 raw suppliers

Chemical Property of 1-(2,2,2-Trifluoroacetyl)pyrrolidin-2-one

Chemical Property:

PSA：37.38000
LogP:0.63560
XLogP3:1.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:0
Exact Mass:181.03506292
Heavy Atom Count:12
Complexity:223

Purity/Quality:

99%+ ^*data from raw suppliers

1-(TRIFLUOROACETYL)-2-PYRROLIDINONE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1CC(=O)N(C1)C(=O)C(F)(F)F

Technology Process of 1-(2,2,2-Trifluoroacetyl)pyrrolidin-2-one

There total 1 articles about 1-(2,2,2-Trifluoroacetyl)pyrrolidin-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 616-45-5
2-pyrrolidinon

: 407-25-0
trifluoroacetic anhydride

: 94363-57-2
1-(trifluoroacetyl)-2-pyrrolidinone

Guidance literature:: In toluene; at 0 - 20 ℃; for 1h;

Reference yield: 35.0%

: 459-57-4
4-fluorobenzaldehyde

: 94363-57-2
1-(trifluoroacetyl)-2-pyrrolidinone

: 1013658-08-6
3-(p-fluorophenylmethyl)-2-pyrrolidinone

Guidance literature:: 4-fluorobenzaldehyde; 1-(trifluoroacetyl)-2-pyrrolidinone; With potassium tert-butylate; In tetrahydrofuran; at 0 - 20 ℃; for 3h; Heating / reflux;

With hydrogen; palladium on carbon; In ethyl acetate; at 20 ℃; for 3h;