1-(4-methoxyphenyl)-1-chloro-2-(4-methoxyphenyl)-2-formylethylene

Base Information

• Chemical Name: 1-(4-methoxyphenyl)-1-chloro-2-(4-methoxyphenyl)-2-formylethylene
• CAS No.: 39831-04-4
• Molecular Formula: C₁₇H₁₅ClO₃
• Molecular Weight: 302.757
• Mol file: 39831-04-4.mol

Synonyms:1-(4-methoxyphenyl)-1-chloro-2-(4-methoxyphenyl)-2-formylethylene

Chemical Property of 1-(4-methoxyphenyl)-1-chloro-2-(4-methoxyphenyl)-2-formylethylene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(4-methoxyphenyl)-1-chloro-2-(4-methoxyphenyl)-2-formylethylene

There total 3 articles about 1-(4-methoxyphenyl)-1-chloro-2-(4-methoxyphenyl)-2-formylethylene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

1,4-di(4-methoxyphenyl)ethanone (120-44-5) + N,N-dimethyl-formamide (68-12-2,33513-42-7) → 1-(4-methoxyphenyl)-1-chloro-2-(4-methoxyphenyl)-2-formylethylene (39831-04-4)

Guidance literature:

With trichlorophosphate; at 0 - 80 ℃;

Reference yield:

(4-Methoxyphenyl)<1-(4-methoxyphenyl)-2-dimethylaminovinyl)>keton (66521-59-3) → 1-(4-methoxyphenyl)-1-chloro-2-(4-methoxyphenyl)-2-formylethylene (39831-04-4)

Guidance literature:

With trichlorophosphate; In dichloromethane; at 20 ℃;

DOI:10.1016/j.tet.2018.04.017

Reference yield:

1,4-di(4-methoxyphenyl)ethanone (120-44-5) → 1-(4-methoxyphenyl)-1-chloro-2-(4-methoxyphenyl)-2-formylethylene (39831-04-4)

Guidance literature:

Multi-step reaction with 2 steps

1: N,N-dimethyl-formamide / 2 h / 100 °C / Microwave irradiation

2: trichlorophosphate / dichloromethane / 20 °C

With trichlorophosphate; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1016/j.tet.2018.04.017

upstream raw materials:

1,4-di(4-methoxyphenyl)ethanone

N,N-dimethyl-formamide

(4-Methoxyphenyl)<1-(4-methoxyphenyl)-2-dimethylaminovinyl)>keton

Downstream raw materials:

α-Mercapto-α'-formyl-4,4'-dimethoxystilben

5-ethxycarbonyl-2,3-bis-(4-methoxyphenyl) thiophene

2,3-Bis(4-methoxyphenyl)thiophene

4,5-bis(4-methoxyphenyl)thiophene-2-carboxylic acid