(3-Phenyl-1,2,4-oxadiazol-5-yl)methanamine

Base Information

Chemical Name:(3-Phenyl-1,2,4-oxadiazol-5-yl)methanamine
CAS No.:90564-77-5
Molecular Formula:C9H9 N3 O
Molecular Weight:175.19
Hs Code.:2934999090
European Community (EC) Number:692-420-1
DSSTox Substance ID:DTXSID10920321
Wikidata:Q82893005
Mol file:90564-77-5.mol

Synonyms:90564-77-5;(3-phenyl-1,2,4-oxadiazol-5-yl)methanamine;(3-phenyl-1,2,4-oxadiazol-5-yl)methylamine;1-(3-phenyl-1,2,4-oxadiazol-5-yl)methanamine;C-(3-Phenyl-[1,2,4]oxadiazol-5-yl)-methylamine;[(3-phenyl-1,2,4-oxadiazol-5-yl)methyl]amine;MFCD06166274;SCHEMBL12477652;DTXSID10920321;HMS1703K18;AKOS003347297;AB23013;VS-0284;BB 0238805;FT-0677693;EN300-27188;F87600;F2147-0559;c-(3-phenyl-[1,2,4]oxadiazol-5-yl)-methylamine, AldrichCPR

Suppliers and Price of (3-Phenyl-1,2,4-oxadiazol-5-yl)methanamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
C-(3-Phenyl-[1,2,4]oxadiazol-5-yl)-methylamine
500mg
$ 109.00

Matrix Scientific
C-(3-Phenyl-[1,2,4]oxadiazol-5-yl)-methylamine
1g
$ 178.00

Matrix Scientific
C-(3-Phenyl-[1,2,4]oxadiazol-5-yl)-methylamine
5g
$ 325.00

Crysdot
(3-Phenyl-1,2,4-oxadiazol-5-yl)methanamine 95+%
5g
$ 310.00

Chemenu
(3-Phenyl-1,2,4-oxadiazol-5-yl)methanamine 95%
5g
$ 290.00

American Custom Chemicals Corporation
N-METHYL-3-PHENYL-1,2,4-OXADIAZOL-5-AMINE 95.00%
5G
$ 1548.26

American Custom Chemicals Corporation
N-METHYL-3-PHENYL-1,2,4-OXADIAZOL-5-AMINE 95.00%
2.5G
$ 1227.82

American Custom Chemicals Corporation
N-METHYL-3-PHENYL-1,2,4-OXADIAZOL-5-AMINE 95.00%
1G
$ 852.55

Alichem
(3-Phenyl-1,2,4-oxadiazol-5-yl)methanamine
5g
$ 341.00

Advanced Chemicals Intermediatesced Chemicals Intermediates
5-Aminomethyl-3-(phenyl)-[1,2,4]oxadiazole;hydrochloride 95%+
5g
$ 572.75

Total 19 raw suppliers

Chemical Property of (3-Phenyl-1,2,4-oxadiazol-5-yl)methanamine

Chemical Property:

Vapor Pressure:0.000229mmHg at 25°C
Refractive Index:1.578
Boiling Point:325.5°C at 760 mmHg
Flash Point:150.7°C
PSA：64.94000
Density:1.217g/cm³
LogP:1.89560
Storage Temp.:2-8°C
Solubility.:DMSO (Slightly), Methanol (Very Slightly)
XLogP3:0.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:175.074561919
Heavy Atom Count:13
Complexity:159

Purity/Quality:

97% ^*data from raw suppliers

C-(3-Phenyl-[1,2,4]oxadiazol-5-yl)-methylamine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:Xi,T
Statements: 25
Safety Statements: 45

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=NOC(=N2)CN
Uses (3-Phenyl-1,2,4-oxadiazol-5-yl)methanamine Hydrochloride is used in preparation of Erythromycin-based macrolides for treatment and/or prevention of infectious diseases.

Technology Process of (3-Phenyl-1,2,4-oxadiazol-5-yl)methanamine

There total 5 articles about (3-Phenyl-1,2,4-oxadiazol-5-yl)methanamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 219611-74-2
2-((3-phenyl-1,2,4-oxadiazol-5-yl)methyl)isoindoline-1,3-dione

: 90564-77-5
(3-phenyl-1,2,4-oxadiazol-5-yl)methylamine

Guidance literature:: With hydrazine hydrate; In ethanol; for 4h; Reflux;

Reference yield:

: 1822-94-2
5-(chloromethyl)-3-phenyl-1,2,4-oxadiazole

: 90564-77-5
(3-phenyl-1,2,4-oxadiazol-5-yl)methylamine

Guidance literature:: Multistep reaction; (i) hexamethylenetetramine, CHCl₃, (ii) aq. HCl, EtOH;
DOI:10.1021/jm50018a009

Reference yield:

: 100-47-0
benzonitrile

: 90564-77-5
(3-phenyl-1,2,4-oxadiazol-5-yl)methylamine

Guidance literature:: Multi-step reaction with 4 steps

1: sodium carbonate; hydroxylamine hydrochloride / water / 10 h / Reflux

2: N-ethyl-N,N-diisopropylamine / dichloromethane / 18 h / Reflux

3: N,N-dimethyl-formamide / 4 h / 60 °C

4: hydrazine hydrate / ethanol / 4 h / Reflux

With hydroxylamine hydrochloride; sodium carbonate; hydrazine hydrate; N-ethyl-N,N-diisopropylamine; In ethanol; dichloromethane; water; N,N-dimethyl-formamide;