3,5-diamino-6-chloro-N-(N-(4-(4-(2-(((2S,3R)-2,3-dihydroxy-3-((4R,5R)-5-hydroxy-2-methyl-1,3-dioxan-4-yl)propyl)(hexyl)amino)ethoxy)phenyl)butyl)carbanmdoyl)pyrazine-2-carboxarnide

Base Information

Chemical Name:3,5-diamino-6-chloro-N-(N-(4-(4-(2-(((2S,3R)-2,3-dihydroxy-3-((4R,5R)-5-hydroxy-2-methyl-1,3-dioxan-4-yl)propyl)(hexyl)amino)ethoxy)phenyl)butyl)carbanmdoyl)pyrazine-2-carboxarnide
CAS No.:1416973-58-4
Molecular Formula:C₃₂H₅₁ClN₈O₇
Molecular Weight:695.259
Hs Code.:

3,5-diamino-6-chloro-N-(N-(4-(4-(2-(((2S,3R)-2,3-dihydroxy-3-((4R,5R)-5-hydroxy-2-methyl-1,3-dioxan-4-yl)propyl)(hexyl)amino)ethoxy)phenyl)butyl)carbanmdoyl)pyrazine-2-carboxarnide

Synonyms:3,5-diamino-6-chloro-N-(N-(4-(4-(2-(((2S,3R)-2,3-dihydroxy-3-((4R,5R)-5-hydroxy-2-methyl-1,3-dioxan-4-yl)propyl)(hexyl)amino)ethoxy)phenyl)butyl)carbanmdoyl)pyrazine-2-carboxarnide

Suppliers and Price of 3,5-diamino-6-chloro-N-(N-(4-(4-(2-(((2S,3R)-2,3-dihydroxy-3-((4R,5R)-5-hydroxy-2-methyl-1,3-dioxan-4-yl)propyl)(hexyl)amino)ethoxy)phenyl)butyl)carbanmdoyl)pyrazine-2-carboxarnide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3,5-diamino-6-chloro-N-(N-(4-(4-(2-(((2S,3R)-2,3-dihydroxy-3-((4R,5R)-5-hydroxy-2-methyl-1,3-dioxan-4-yl)propyl)(hexyl)amino)ethoxy)phenyl)butyl)carbanmdoyl)pyrazine-2-carboxarnide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3,5-diamino-6-chloro-N-(N-(4-(4-(2-(((2S,3R)-2,3-dihydroxy-3-((4R,5R)-5-hydroxy-2-methyl-1,3-dioxan-4-yl)propyl)(hexyl)amino)ethoxy)phenyl)butyl)carbanmdoyl)pyrazine-2-carboxarnide

There total 5 articles about 3,5-diamino-6-chloro-N-(N-(4-(4-(2-(((2S,3R)-2,3-dihydroxy-3-((4R,5R)-5-hydroxy-2-methyl-1,3-dioxan-4-yl)propyl)(hexyl)amino)ethoxy)phenyl)butyl)carbanmdoyl)pyrazine-2-carboxarnide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 76942-92-2
methyl 3,5-diamino-6-chloropyrazine-2-carbonylcarbamimidothioate hydroiodic acid salt

: (1R,2S)-3((2-(4-(4-aminobutyl)phenoxy)ethyl)(hexyl)amino)-1-((4R,5R)-5-hydroxy-2-methyl-1,3-dioxan-4yl)propane-1,2-diol acetic acid

: 1416973-58-4
3,5-diamino-6-chloro-N-(N-(4-(4-(2-(((2S,3R)-2,3-dihydroxy-3-((4R,5R)-5-hydroxy-2-methyl-1,3-dioxan-4-yl)propyl)(hexyl)amino)ethoxy)phenyl)butyl)carbanmdoyl)pyrazine-2-carboxarnide

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In ethanol; at 0 - 20 ℃; for 2h; Sealed tube;

Reference yield:

: 587880-55-5
{4-[4-(2-tert-Butoxycarbonylaminoethoxy)phenyl]butyl}carbamic acid benzyl ester

: 1416973-58-4
3,5-diamino-6-chloro-N-(N-(4-(4-(2-(((2S,3R)-2,3-dihydroxy-3-((4R,5R)-5-hydroxy-2-methyl-1,3-dioxan-4-yl)propyl)(hexyl)amino)ethoxy)phenyl)butyl)carbanmdoyl)pyrazine-2-carboxarnide

Guidance literature:: Multi-step reaction with 5 steps

1.1: hydrogenchloride / 1,4-dioxane / 1 h / 20 °C

2.1: methanol / 0.5 h / 20 °C

2.2: 16 h / 20 °C

3.1: sodium cyanoborohydride; acetic acid / methanol / 16 h / 20 °C

4.1: acetic acid; palladium 10% on activated carbon; hydrogen / methanol / 6 h / 20 °C / 760.05 Torr

5.1: N-ethyl-N,N-diisopropylamine / ethanol / 2 h / 0 - 20 °C / Sealed tube

With hydrogenchloride; palladium 10% on activated carbon; hydrogen; sodium cyanoborohydride; acetic acid; N-ethyl-N,N-diisopropylamine; In 1,4-dioxane; methanol; ethanol;

Reference yield:

: benzyl 4-(4-3(((2S,3R)-2,3-dihydroxy-3((4R,5R)-5-hydroxy-2-methyl-1,3-dioxan-4yl)propylamino)propoxy)phenyl)butylcarbamate

: 1416973-58-4
3,5-diamino-6-chloro-N-(N-(4-(4-(2-(((2S,3R)-2,3-dihydroxy-3-((4R,5R)-5-hydroxy-2-methyl-1,3-dioxan-4-yl)propyl)(hexyl)amino)ethoxy)phenyl)butyl)carbanmdoyl)pyrazine-2-carboxarnide

Guidance literature:: Multi-step reaction with 3 steps

1: sodium cyanoborohydride; acetic acid / methanol / 16 h / 20 °C

2: acetic acid; palladium 10% on activated carbon; hydrogen / methanol / 6 h / 20 °C / 760.05 Torr

3: N-ethyl-N,N-diisopropylamine / ethanol / 2 h / 0 - 20 °C / Sealed tube

With palladium 10% on activated carbon; hydrogen; sodium cyanoborohydride; acetic acid; N-ethyl-N,N-diisopropylamine; In methanol; ethanol;