(10R,13S)-13-(hydroxymethyl)-9-methyl-10-propan-2-yl-3,9,12-triazatricyclo[6.6.1.04,15]pentadeca-1,4(15),5,7-tetraen-11-one

Base Information

Chemical Name:(10R,13S)-13-(hydroxymethyl)-9-methyl-10-propan-2-yl-3,9,12-triazatricyclo[6.6.1.04,15]pentadeca-1,4(15),5,7-tetraen-11-one
CAS No.:90365-56-3
Molecular Formula:C₁₇H₂₃N₃O₂
Molecular Weight:301.389
Hs Code.:
European Community (EC) Number:635-864-3
Nikkaji Number:J805.492D
Mol file:90365-56-3.mol

Synonyms:90365-56-3

Suppliers and Price of (10R,13S)-13-(hydroxymethyl)-9-methyl-10-propan-2-yl-3,9,12-triazatricyclo[6.6.1.04,15]pentadeca-1,4(15),5,7-tetraen-11-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(+)-IndolactamV
5mg
$ 2415.00

TRC
(+)-IndolactamV
2.5mg
$ 1295.00

American Custom Chemicals Corporation
(+)-INDOLACTAM V 95.00%
1MG
$ 771.31

Total 5 raw suppliers

Chemical Property of (10R,13S)-13-(hydroxymethyl)-9-methyl-10-propan-2-yl-3,9,12-triazatricyclo[6.6.1.04,15]pentadeca-1,4(15),5,7-tetraen-11-one

Chemical Property:

Boiling Point:584.0±50.0 °C(Predicted)
PKA:14.39±0.10(Predicted)
PSA：68.36000
Density:1.166±0.06 g/cm3(Predicted)
LogP:2.05570
Storage Temp.:-20°C
XLogP3:2.3
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:301.17902698
Heavy Atom Count:22
Complexity:415

Purity/Quality:: (+)-IndolactamV ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi
Hazard Codes:Xi
Statements: 36/37/38
Safety Statements: 26-36

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)C1C(=O)NC(CC2=CNC3=C2C(=CC=C3)N1C)CO
Isomeric SMILES:CC(C)[C@@H]1C(=O)N[C@@H](CC2=CNC3=C2C(=CC=C3)N1C)CO
Uses (+)?-?Indolactam-?V isomer shows no induction of ornithine decarboxylase, unlike some of its other analogs.

Technology Process of (10R,13S)-13-(hydroxymethyl)-9-methyl-10-propan-2-yl-3,9,12-triazatricyclo[6.6.1.04,15]pentadeca-1,4(15),5,7-tetraen-11-one

There total 268 articles about (10R,13S)-13-(hydroxymethyl)-9-methyl-10-propan-2-yl-3,9,12-triazatricyclo[6.6.1.04,15]pentadeca-1,4(15),5,7-tetraen-11-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: (2S,5S)-(-)-5-(hydroxymethyl)-2-isopropyl-1-methyl-8-tosyl-4,5,6,8-tetrahydro-1H-[1,4]diazonino[7,6,5-cd]indol-3(2H)-one

: 84590-48-7,84622-58-2,90365-54-1,90365-55-2,90365-56-3,132341-58-3,90365-57-4
indolactam V

Guidance literature:: With ammonium chloride; magnesium; In ethanol; at 20 ℃; for 48h;
DOI:10.1016/j.tet.2015.04.015

Reference yield: 99.0%

: 148153-23-5
(10S,13S)-10-Isopropyl-9-methyl-11-oxo-3,9,12-triaza-tricyclo[6.6.1.0^4,15]pentadeca-1,4⁽¹⁵⁾,5,7-tetraene-13-carboxylic acid methyl ester

: 84590-48-7,84622-58-2,90365-54-1,90365-55-2,90365-56-3,132341-58-3,90365-57-4
indolactam V

Guidance literature:: With lithium borohydride; In tetrahydrofuran; at 20 ℃; for 5h; Glovebox; Inert atmosphere; Sealed tube;
DOI:10.1021/acs.orglett.6b00614