3-benzyl-6,7-dihydroxy-4-(4-methoxyphenyl)-1-methyl-1H-naphtho[2,3-d]imidazole-2,5,8-trione

Base Information

Chemical Name:3-benzyl-6,7-dihydroxy-4-(4-methoxyphenyl)-1-methyl-1H-naphtho[2,3-d]imidazole-2,5,8-trione
CAS No.:1373395-22-2
Molecular Formula:C₂₆H₂₀N₂O₆
Molecular Weight:456.455
Hs Code.:

Synonyms:3-benzyl-6,7-dihydroxy-4-(4-methoxyphenyl)-1-methyl-1H-naphtho[2,3-d]imidazole-2,5,8-trione

Suppliers and Price of 3-benzyl-6,7-dihydroxy-4-(4-methoxyphenyl)-1-methyl-1H-naphtho[2,3-d]imidazole-2,5,8-trione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3-benzyl-6,7-dihydroxy-4-(4-methoxyphenyl)-1-methyl-1H-naphtho[2,3-d]imidazole-2,5,8-trione

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3-benzyl-6,7-dihydroxy-4-(4-methoxyphenyl)-1-methyl-1H-naphtho[2,3-d]imidazole-2,5,8-trione

There total 10 articles about 3-benzyl-6,7-dihydroxy-4-(4-methoxyphenyl)-1-methyl-1H-naphtho[2,3-d]imidazole-2,5,8-trione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

: 4845-50-5
2,3-dihydroxy-1,4-dioxane

: 1373395-21-1
3-benzyl-4-(4-methoxyphenyl)-1-methyl-2-oxo-2,3-dihydro-1H-benzo[d]imidazole-5,6-dicarbaldehyde

: 1373395-22-2
3-benzyl-6,7-dihydroxy-4-(4-methoxyphenyl)-1-methyl-1H-naphtho[2,3-d]imidazole-2,5,8-trione

Guidance literature:: With potassium cyanide; potassium carbonate; In tetrahydrofuran; water; at 20 ℃; for 0.0833333h;
DOI:10.1021/ol300704w

Reference yield:

: 1186662-54-3
3-benzyl-4-(4-methoxyphenyl)-3,7,7a,8-tetrahydro-5H-furo-[3,4-f]benzimidazol-5-one

: 1373395-22-2
3-benzyl-6,7-dihydroxy-4-(4-methoxyphenyl)-1-methyl-1H-naphtho[2,3-d]imidazole-2,5,8-trione

Guidance literature:: Multi-step reaction with 6 steps

1: manganese(IV) oxide / dichloromethane / 24 h / 20 °C

2: toluene / 24 h / 120 °C

3: sodium hypochlorite / tetrahydrofuran / 0.5 h / 0 - 20 °C

4: diisobutylaluminium hydride / hexane; dichloromethane / 4 h / -78 - 20 °C / Inert atmosphere

5: N-(tert-butyl)benzenesulfinimidoyl chloride; 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane / 0.5 h / -78 °C / Inert atmosphere

6: potassium cyanide; potassium carbonate / tetrahydrofuran; water / 0.08 h / 20 °C

With potassium cyanide; manganese(IV) oxide; sodium hypochlorite; N-(tert-butyl)benzenesulfinimidoyl chloride; diisobutylaluminium hydride; potassium carbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; hexane; dichloromethane; water; toluene;
DOI:10.1021/ol300704w

Reference yield:

: 1341165-32-9
3-benzyl-4-(4-methoxyphenyl)-1-methyl-3,7-dihydro-1H-furo[3,4-f]benzimidazole-2,5-dione

: 1373395-22-2
3-benzyl-6,7-dihydroxy-4-(4-methoxyphenyl)-1-methyl-1H-naphtho[2,3-d]imidazole-2,5,8-trione

Guidance literature:: Multi-step reaction with 3 steps

1: diisobutylaluminium hydride / hexane; dichloromethane / 4 h / -78 - 20 °C / Inert atmosphere

2: N-(tert-butyl)benzenesulfinimidoyl chloride; 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane / 0.5 h / -78 °C / Inert atmosphere

3: potassium cyanide; potassium carbonate / tetrahydrofuran; water / 0.08 h / 20 °C

With potassium cyanide; N-(tert-butyl)benzenesulfinimidoyl chloride; diisobutylaluminium hydride; potassium carbonate; 1,8-diazabicyclo[5.4.0]undec-7-ene; In tetrahydrofuran; hexane; dichloromethane; water;
DOI:10.1021/ol300704w