1341165-32-9Relevant academic research and scientific papers
Total synthesis of 7′-desmethylkealiiquinone, 4′- desmethoxykealiiquinone, and 2-deoxykealiiquinone
Lima, Heather M.,Sivappa, Rasapalli,Yousufuddin, Muhammed,Lovely, Carl J.
, p. 2481 - 2490 (2014/04/17)
Synthetic approaches to the imidazonaphthoquinone core of kealiiquinone and related Leucetta-derived alkaloids are described. The polysubstituted benzimidazole framework can be constructed through intramolecular Diels-Alder reactions of propiolate-derived
Total synthesis of 7′-desmethylkealiiquinone
Lima, Heather M.,Sivappa, Rasapalli,Yousufuddin, Muhammed,Lovely, Carl J.
supporting information; experimental part, p. 2274 - 2277 (2012/06/30)
The total synthesis of an analogue of the marine alkaloid kealiiquinone has been completed through application of an intramolecular Diels-Alder reaction of an imidazole-containing enyne. Oxidative aromatization of the lactone adduct and N-methylation faci
Synthesis of 2-imidazolones and 2-iminoimidazoles
Lima, Heather M.,Lovely, Carl J.
supporting information; experimental part, p. 5736 - 5739 (2011/12/05)
Convenient methods for the direct conversion of imidazolium salts to the corresponding 2-imidazolone or 2-imino imidazole derivatives have been developed. Treatment of the salt with commercial bleach leads to effective oxidation at C2 and the formation of the corresponding imidazolone. Alternatively, treatment of the salt with an N-chloro amide affords the corresponding protected 2-amino derivative in good yield.
