2-(2-acetylphenyl)-2,2-dimethylacetic acid

Base Information

Chemical Name:2-(2-acetylphenyl)-2,2-dimethylacetic acid
CAS No.:91496-72-9
Molecular Formula:C₁₂H₁₄O₃
Molecular Weight:206.241
Hs Code.:

Synonyms:2-(2-acetylphenyl)-2,2-dimethylacetic acid

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Chemical Property of 2-(2-acetylphenyl)-2,2-dimethylacetic acid

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Technology Process of 2-(2-acetylphenyl)-2,2-dimethylacetic acid

There total 5 articles about 2-(2-acetylphenyl)-2,2-dimethylacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 57625-74-8
methyl 2-methyl-2-phenylpropionate

: 75-36-5
acetyl chloride

: 91496-72-9
2-(2-acetylphenyl)-2,2-dimethylacetic acid

: 857768-18-4
2-(4-acetyl-phenyl)-2-methyl-propionic acid

Guidance literature:: methyl 2-methyl-2-phenylpropionate; acetyl chloride; With aluminum (III) chloride; In carbon disulfide; at -10 - 45 ℃; for 15h;

With sodium hydroxide; In tetrahydrofuran; at 0 - 20 ℃; Overall yield = 99 percent; Overall yield = 14 g;

Reference yield:

: 2177-45-9
1,1,3-trimethylindene

: 91496-72-9
2-(2-acetylphenyl)-2,2-dimethylacetic acid

Guidance literature:: With sodium dichromate; sulfuric acid;
DOI:10.1021/jo01065a050

Reference yield:

: 105337-69-7
1,3,3-Trimethyl-indan-1-ol

: 91496-72-9
2-(2-acetylphenyl)-2,2-dimethylacetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: aq. H₂SO₄ / Heating

2: Na₂Cr₂O₇, aq. H₂SO₄

With sodium dichromate; sulfuric acid;
DOI:10.1021/jo01065a050