1,1,3-TRIMETHYLINDENE

Base Information

• Chemical Name: 1,1,3-TRIMETHYLINDENE
• CAS No.: 2177-45-9
• Molecular Formula: C12H14
• Molecular Weight: 158.243
• Mol file: 2177-45-9.mol

Synonyms:Indene,1,1,3-trimethyl- (6CI,7CI,8CI); 1,1,3-Trimethyl-1H-indene;1,1,3-Trimethylindene

Chemical Property of 1,1,3-TRIMETHYLINDENE

Chemical Property:

• Boiling Point: 120-124 °C(Press: 0.1 Torr)
• PSA: 0.00000
• Density: 0.940±0.06 g/cm3(Predicted)
• LogP: 3.38110
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

1,1,3-Trimethyl-1H-indene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1,1,3-TRIMETHYLINDENE

There total 2 articles about 1,1,3-TRIMETHYLINDENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-nitropropane (79-46-9) + benzene (71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1) → Isopropylbenzene (98-82-8) + 1,1,3-trimethylindene (2177-45-9) + 1,1,3-trimethyl-3-phenylindane (3910-35-8) + 2,2-diphenylpropane (778-22-3) + 3,3,3',3'-tetramethyl-1,1'-spiro-biindane (32507-26-9,58343-29-6) + 1',3,3,3',3'-pentamethyl-1-(1'-indanyl-methylene)-indane (13864-90-9)

Guidance literature:

With aluminium trichloride; Product distribution; Mechanism; 2 h, room temp., 55 deg C, various periods of time;

DOI:10.1016/S0040-4020(01)92438-X

Reference yield:

dimethylsulfone (67-71-0) + 1-Methylinden (767-59-9) → 1,1,3-trimethylindene (2177-45-9) + 1,1-dimethyl-1H-indene (18636-55-0) + 1,3-dimethyl-1H-indene (2177-48-2)

Guidance literature:

With n-butyllithium; Yield given. Multistep reaction. Yields of byproduct given; 1.) diethyl ether, n-hexane, room temp., 0.5 h, 2.) room temp., 5 h;

DOI:10.1021/jo00345a031

Reference yield:

1,1,3-trimethylindene (2177-45-9) → 2-(2-acetylphenyl)-2,2-dimethylacetic acid (91496-72-9)

Guidance literature:

With sodium dichromate; sulfuric acid;

DOI:10.1021/jo01065a050

upstream raw materials:

dimethylsulfone

1-Methylinden

2-nitropropane

benzene

Downstream raw materials:

3,3-Dimethyl-3',3'-diphenyl-1,1'-spirobiindan

2-(2-acetylphenyl)-2,2-dimethylacetic acid